Tissue Loss, Processing Time, and Primary Graft Failure in Eye Bank–Prepared Descemet Membrane Endothelial Keratoplasty Grafts Before and After Prestripped to Preloaded Graft Transition

Cornea ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Andrew T. Duong ◽  
Lindsay Mandel Foley ◽  
Joshua Galloway ◽  
Christopher S. Sales ◽  
Khoa D. Tran
Keyword(s):  
Graft Failure ◽  
Processing Time ◽  
Tissue Loss ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Eye Bank ◽  
Descemet Membrane ◽  
Before And After ◽  
Primary Graft Failure

Impact of Introducing 2 Simple Technique Modifications on the Descemet Membrane Endothelial Keratoplasty Learning Curve

2016 ◽  
Vol 27 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Francisco Arnalich-Montiel ◽  
Ane Pérez-Sarriegui ◽  
Alfonso Casado
Keyword(s):  
Learning Curve ◽  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Primary Graft Failure ◽  
Air Tamponade ◽  
Group 2 ◽  
The Impact ◽  
Group 1

Purpose To analyze the impact of performing premarking of the Descemet roll and using SF6 20% on a surgeon's Descemet membrane endothelial keratoplasty (DMEK) learning process. Methods A total of 30 consecutive eyes with endothelial dysfunction undergoing DMEK during the learning curve of a surgeon were retrospectively analyzed. Prior to the study, the surgeon had already performed 10 DMEKs. The first 15 consecutive patients were included in group 1 (no premarking and air tamponade) and the other 15 consecutive patients were included in group 2 (premarking and SF6 tamponade). Main outcome parameters were best-corrected visual acuity (BCVA), endothelial cell density (ECD) loss at 6 months, and intraoperative and postoperative complications. Results Among the 2 groups, BCVA and ECD loss at 6 months were similar. However, there was a statistically significant reduction in primary graft failure (40% vs 0%) and need of rebubbling due to complete or partial graft detachment (40% vs 6%) when comparing group 1 versus group 2. In group 1, half of the patients needing rebubbling had primary graft failure. Conclusions Based on our personal experience, premarking the graft to assess orientation and using a SF6 gas tamponade dramatically reduces the risk of primary graft failure and the need for rebubbling even during the first stages of the learning curve. These findings should encourage surgeons to safely change from Descemet stripping automated endothelial keratoplasty to DMEK.

Descemet Membrane Endothelial Keratoplasty as Treatment for Graft Failure After Descemet Stripping Automated Endothelial Keratoplasty

2015 ◽  
Vol 159 (6) ◽  
pp. 1050-1057.e2 ◽  
Author(s):  
Julia M. Weller ◽  
Theofilos Tourtas ◽  
Friedrich E. Kruse ◽  
Ursula Schlötzer-Schrehardt ◽  
Thomas Fuchsluger ◽  
...  
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane

scholarly journals Ultrastructural findings in graft failure after Descemet membrane endothelial keratoplasty (DMEK) and new triple procedure

Medicine ◽  
2019 ◽  
Vol 98 (19) ◽  
pp. e15493 ◽  
Author(s):  
Isabell Schmidt ◽  
Ursula Schlötzer-Schrehardt ◽  
Achim Langenbucher ◽  
Timo Eppig ◽  
Tobias Hager ◽  
...  
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Triple Procedure ◽  
Ultrastructural Findings

scholarly journals Bubble technique for Descemet membrane endothelial keratoplasty tissue preparation in an eye bank: air or liquid?

2014 ◽  
Vol 93 (2) ◽  
pp. e129-e134 ◽  
Author(s):  
Alessandro Ruzza ◽  
Mohit Parekh ◽  
Gianni Salvalaio ◽  
Stefano Ferrari ◽  
Davide Camposampiero ◽  
...  
Keyword(s):  
Tissue Preparation ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Eye Bank ◽  
Descemet Membrane

Dark Endothelial Spots After Descemet Membrane Endothelial Keratoplasty May Appear as Recurrent Fuchs Dystrophy or Herald Graft Failure or Rejection

Cornea ◽  
2017 ◽  
Vol 36 (12) ◽  
pp. 1480-1485 ◽  
Author(s):  
Vasiliki Zygoura ◽  
Lamis Baydoun ◽  
Claire Monnereau ◽  
Maria Satué ◽  
Silke Oellerich ◽  
...  
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Fuchs Dystrophy

scholarly journals Chord Mu (µ) and Chord Alpha (α) Length Changes in Fuchs Endothelial Corneal Dystrophy before and after Descemet Membrane Endothelial Keratoplasty (DMEK) Surgery

2021 ◽  
Vol 10 (21) ◽  
pp. 4844
Author(s):  
Carlos Rocha-de-Lossada ◽  
José-María Sánchez-González ◽  
Davide Borroni ◽  
Víctor Llorens-Bellés ◽  
Rahul Rachwani-Anil ◽  
...  
Keyword(s):  
Corneal Dystrophy ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Post Surgery ◽  
Before And After ◽  
Length Changes ◽  
Corneal Apex ◽  
Center Distance

This paper will evaluate chord mu and alpha length in patients with Fuchs endothelial corneal dystrophy (FECD) and its changes following Descemet membrane endothelial keratoplasty (DMEK). Patients with FECD that underwent DMEK surgery were included in this retrospective study. Scheimpflug Tomography was carried out in order to calculate chord mu and chord alpha lengths prior to surgery and at 3 and 12 months postoperative. This study included 27 eyes from 27 patients. Significant changes in chord mu were observed within the first three months (from 0.47 ± 0.32 to 0.29 ± 0.21 mm, p < 0.01) and remained stable 12 months postoperative (0.30 ± 0.21 mm, p > 0.05). However, chord alpha remained stable throughout the 12 months post surgery (from 0.53 ± 0.19 to 0.49 ± 0.14 mm, p > 0.05). In addition to the pupillary center distance from the corneal apex (from 0.35 ± 0.25 to 0.34 ± 0.20 mm, p > 0.05) also remain stable. In FECD patients undergoing DMEK surgery, chord mu length decreased, and chord alpha length remained stable after 12 months of follow-up.

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