Topical Insulin—Utility and Results in Refractory Neurotrophic Keratopathy in Stages 2 and 3

Cornea ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ricardo José dos Santos Machado Soares ◽  
Carlos Arêde ◽  
Filipe Sousa Neves ◽  
Joana da Silva Fernandes ◽  
Catarina Cunha Ferreira ◽  
...  
2021 ◽  
Vol 20 ◽  
pp. 163-172
Author(s):  
Catherine Y. Liu ◽  
Andrea C. Arteaga ◽  
Sammie E. Fung ◽  
M. Soledad Cortina ◽  
Ilya M. Leyngold ◽  
...  

2021 ◽  
Vol 22 ◽  
pp. 143-151
Author(s):  
Leyla Yavuz Saricay ◽  
Betul N. Bayraktutar ◽  
Brendan M. Kenyon ◽  
Pedram Hamrah

2018 ◽  
Vol 103 (9) ◽  
pp. 1235-1238 ◽  
Author(s):  
Nate Jowett ◽  
Roberto Pineda II

Background/AimsMedical management of neurotrophickeratopathy is challenging and costly. Supra-orbital nerve transfer to thecornea has proven effective for management of keratopathy, but yieldsconsiderable donor site morbidity. Herein, a novel technique for reinnervationof the anaesthetic cornea is presented and early results characterised.MethodsSensory fibres of the ipsilateral greatauricular nerve were directed via an interposition graft to the anteriorcorneal stroma using scleral-corneal tunnel incisions in two patients withgrade III neurotrophic keratopathy.ResultsImprovements in visual acuity, cornealpachymetry, corneal esthesiometry, and corneal neurotisation as assessed by invivo confocal microscopy were observed within nine months of surgery in bothpatients.ConclusionCorneal neurotisation by interposition grafttransfer of great auricular nerve fibres via scleral-corneal tunnel incisionsappears effective in the management of neurotrophic keratopathy.


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