131 Background: Factors associated with pursuit of active surveillance in men with low-risk prostate cancer are not well-delineated. Methods: 701 patients with low-risk prostate cancer (clinical stage < T2b, Gleason score < 7, and PSA < 10 ng/mL), treated in 2009 at three tertiary care centers affiliated with the same medical school and within the same health care system were identified. All patients were evaluated by one or more urological, radiation, and/or medical oncologists specializing in genitourinary malignancies, either sequentially at independent appointments with differing dates/locations, or concurrently at a multidisciplinary genitourinary oncology clinic in which all three specialists evaluated the patient jointly during a single visit. Pre-treatment and treatment-related variables were recorded. Logistic regression was performed to identify demographic and clinical factors associated with the employment of active surveillance. Results: Forty three percent of patients referred to a multidisciplinary clinic underwent active surveillance, as opposed to 22% of patients seen by individual practitioners (p<.001). On multivariate logistic regression, older age (OR 1.09 (per year), p <.001), increased comorbidities (OR 1.41 (per unit increase in Charlson score), p=.01), unmarried social status (OR 1.76, p=.04), a smaller percentage of positive cores (OR 0.92 (per percent core increase), p<.001), and referral to a multidisciplinary clinic (OR 2.22, p<.01) were all significantly associated with pursuit of active surveillance. The number of physicians or specialities seen in consultation was not significantly associated with pursuit of active surveillance. Conclusions: Older age, increased comorbidities, unmarried social status, and a smaller percentage of positive cores are associated with pursuit of active surveillance. Notably, referral to a multidisciplinary genitourinary oncology clinic significantly increases rates of active surveillance in men with low-risk prostate cancer, implying that the multidisciplinary clinic itself, and not merely the number or type of physicians seen, is important to the shared decision making process for a patient to elect active surveillance.
MP23-18 FACTORS ASSOCIATED WITH LONG-TERM ADHERENCE TO ACTIVE SURVEILLANCE AMONG MEN WITH LOW RISK PROSTATE CANCER