Quality of Life in Vulvar Lichen Sclerosus Patients Treated With Long-Term Topical Corticosteroids

2021 ◽  
Vol 25 (2) ◽  
pp. 158-165
Author(s):  
Marlene Wijaya ◽  
Geoffrey Lee ◽  
Gayle Fischer ◽  
Andrew Lee
Keyword(s):  
Quality Of Life ◽  
Lichen Sclerosus ◽  
Topical Corticosteroids ◽  
Vulvar Lichen Sclerosus

The effect of vulvar lichen sclerosus on quality of life and sexual functioning

2010 ◽  
Vol 31 (4) ◽  
pp. 279-284 ◽  
Author(s):  
Hedwig P Van De Nieuwenhof ◽  
Kim A. P. Meeuwis ◽  
Theodoor E. Nieboer ◽  
Marianne C. M. Vergeer ◽  
Leon F. A. G. Massuger ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Functioning ◽  
Lichen Sclerosus ◽  
Vulvar Lichen Sclerosus

scholarly journals Efficiency of Liposomal Gelcoat with Dihydroquercetin Flamena in Therapy of Vulvar Lichen Sclerosus

Doctor Ru ◽  
2021 ◽  
Vol 20 (6) ◽  
pp. 102-106
Author(s):  
N.I. Chernova ◽  
◽  
I.S. Zadorozhnaya ◽  
Keyword(s):  
Quality Of Life ◽  
Combination Therapy ◽  
Lichen Sclerosus ◽  
Study Objective ◽  
White Spots ◽  
Study Results ◽  
Group 2 ◽  
Vulvar Lichen Sclerosus ◽  
Group 1

Study Objective: To assess the therapeutic efficiency of liposomal gelcoat with dihydroquercetin Flamena in combination therapy of vulvar lichen sclerosus (VLS). Study Design: open comparative perspective study. Materials and Methods. The study included 52 patients with VLS aged 22 to 65 years. Patients were randomised into two therapeutic groups: 27 patients in group 1 had a standard course of therapy with ultrapotent topic glucocorticosteroids (tGCS) for 3 months; 25 patients in group 2 had a standard intermittent 3-month therapy with Flamena gel for 1.5 month. Therapy efficiency was evaluated using the Dermatological Symptom Scale, visual analogue scale, and Dermatological Quality of Life Index (DQoLI). Therapeutic manipulations were assessed during 6 visits. Study Results. Flamena gel facilitated clinical remission maintenance and prolongation. Starting from visit 4, there were differences between group 1 and group 2 values. By visit 5, group 2 patients demonstrated stable regression or reduction in white spots and papules/plaques (not more than 0.8 ± 0.35 and 0.5 ± 0.26 points, respectively). At the same time, group 1 had clinical symptoms intensity rising to 1.6 ± 0.87 points (white spots) and 1.2 ± 0.9 points (papules/plaques), correlating with subjective symptoms aggravation. Effects of therapy on DQoLI were demonstrated with reduction in mean values to 4.2 ± 2.6 points (group 1) and 3.2 ± 1.4 points (group 2) by visit 2. In group 2, the values remained at 3.3 ± 0.6 points by day 60 (visit 6) of follow-up, whereas in group 1 the VLS impact over quality of life increased from mild (4.2 ± 2.6 points — visit 2) to moderate (7.1 ± 2.3 points — visit 6) in a majority of study subjects. Conclusion. A comparative study demonstrated a marked therapeutic effect and high safety profile of Flamena gel in a combination therapy of VLS patients. It improves disease prognosis due to antiinflammatory, antiseptic and regenerative action, thus allowing reducing the frequency and amount of tGCS use. Keywords: vulvar lichen sclerosus, Flamena gel, vulvar itching

scholarly journals Psycho-emotional profile of patients with vulvar lichen sclerosus

2020 ◽  
Vol 14 (2) ◽  
pp. 203-210
Author(s):  
A. G. Solopova ◽  
E. E. Achkasov ◽  
A. D. Makatsariya ◽  
V. S. Moskvichyova ◽  
A. E. Ivanov
Keyword(s):  
Quality Of Life ◽  
Depressive Disorders ◽  
Life Quality ◽  
Depression Scale ◽  
Lichen Sclerosus ◽  
Well Being ◽  
Control Group ◽  
Significant Deterioration ◽  
Vulvar Lichen Sclerosus

Aim: to assess the psycho-emotional profile in patients with vulvar lichen sclerosus.Materials and methods. We examined 57 patients with a diagnosis of vulvar lichen sclerosus, the average age of 35.0 ± 0.6 (from 18 to 45) years. The control group included 45 healthy women without dystrophic changes in the external genital organs, who applied for a routine examination. The following methods were used to analyze the psycho-emotional profile: WAM questionnaire (well-being, activity, mood), Hospital Anxiety and Depression Scale (HADS), the Dermatology Life Quality Index (DLQI).Results. In patients with vulvar lichen sclerosus a decrease in indicators “well-being” (24.3 ± 1.7 versus 52.4 ± 5.6 scores) and “mood” (28.7 ± 3.6 versus 58.1 ± 6.1 scores) was revealed; “activity” was changed slightly (41.2 ± 3.2 against 47.4 ± 4.9 scores). Depressive (75.4 % versus 15.6 %) and anxiety (68.4 % versus 20 %) disorders were also more common in this group. Significant deterioration in the quality of life in patients was confirmed by a DIQL (18.79 ± 4.98 scores).Conclusion. Psycho-emotional profile of patients with vulvar lichen sclerosus is characterized by a change in most of the analyzed parameters. The presence of anxiety-depressive disorders can aggravate both the general somatic state and the course of the underlying disease. So activities aimed at improving the quality of life should be included in the rehabilitation of these patients.

scholarly journals The effect of vulvar lichen sclerosus on quality of life and sexual functioning

2021 ◽  
Vol 5 (7) ◽  
pp. 691-694
Author(s):  
Özlem HELVACİOGLU ◽  
Zeynep TOPKARCI ◽  
Çağlar HELVACIOĞLU ◽  
Ayşe KAVAK
Keyword(s):  
Quality Of Life ◽  
Sexual Functioning ◽  
Lichen Sclerosus ◽  
Vulvar Lichen Sclerosus

Thinking Beyond Language: Intervention for Severe Aphasia

2009 ◽  
Vol 19 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Nina Simmons-Mackie
Keyword(s):  
Quality Of Life ◽  
Communication Training ◽  
Language Intervention ◽  
Specific Training ◽  
Environmental Support ◽  
Total Communication ◽  
Communication Partners

Abstract Purpose: This article addresses several intervention approaches that aim to improve life for individuals with severe aphasia. Because severe aphasia significantly compromises language, often for the long term, recommended approaches focus on additional domains that affect quality of life. Treatments are discussed that involve increasing participation in personally relevant life situations, enhancing environmental support for communication and participation, and improving communicative confidence. Methods: Interventions that have been suggested in the aphasia literature as particularly appropriate for people with severe aphasia include training in total communication, training of communication partners, and activity specific training. Conclusion: Several intervention approaches can be implemented to enhance life with severe aphasia.

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