Association study of methylenetetrahydrofolate reductase C677T mutation with cerebral venous thrombosis in an Iranian population

2015 ◽  
Vol 26 (8) ◽  
pp. 869-873 ◽  
Author(s):  
Habib Ghaznavi ◽  
Zahra Soheili ◽  
Shahram Samiei ◽  
Mohammad S. Soltanpour
Keyword(s):  
Venous Thrombosis ◽  
Association Study ◽  
Cerebral Venous Thrombosis ◽  
Methylenetetrahydrofolate Reductase ◽  
Iranian Population ◽  
C677t Mutation

scholarly journals The Association Between Common C677T Mutation in Methylenetetrahydrofolate Reductase Gene and the Risk of Venous Thrombosis in an Iranian Population

2008 ◽  
Vol 39 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Mohammad Soleyman Soltanpour ◽  
Zahra Soheili ◽  
Ali Akbar Pourfathollah ◽  
Shahram Samiei ◽  
Reza Meshkani ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Methylenetetrahydrofolate Reductase ◽  
Iranian Population ◽  
Reductase Gene ◽  
C677t Mutation ◽  
Methylenetetrahydrofolate Reductase Gene

scholarly journals Cerebral Venous Thrombosis after a Cesarean Delivery

2010 ◽  
Vol 53 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Edvard Ehler ◽  
Aleš Kopal ◽  
Milan Mrklovský ◽  
Milan Košťál
Keyword(s):  
Risk Factors ◽  
Molecular Weight ◽  
Venous Thrombosis ◽  
Cesarean Delivery ◽  
Cerebral Venous Thrombosis ◽  
Low Molecular Weight Heparin ◽  
Methylenetetrahydrofolate Reductase ◽  
Low Molecular Weight ◽  
Viii Level ◽  
Risk Patients

Cerebral venous thrombosis (CVT) is a serious condition affecting mostly women. This report concerns two cases of women who developed CVT within 14 days of cesarean delivery. Magnetic resonance angiography of the brain (venous phase) is the best modality to diagnose the condition, and parenteral application of low-molecular-weight heparin is the most beneficial treatment. The first patient was found to have an elevated factor VIII level. In the second patient, homozygosity of the C677T mutation in the 5,10-methylenetetrahydrofolate reductase gene was found. The puerperal period and Cesarean Section (CS) are risk factors for thrombotic complications, including CVT. It is necessary to search for risk factors in a patient’s history and within the group of at-risk patients to prolong preventive administration of low molecular weight heparin (LMWH). CVT (including puerperium related) is not a detrimental to future pregnancies.

Role of methylenetetrahydrofolate reductase A1298C polymorphism in cerebral venous thrombosis

2013 ◽  
pp. 1 ◽  
Author(s):  
Najiba Fekih-Mrissa ◽  
Sarra Klai ◽  
Meriem Mrad ◽  
Jamel Zaouali ◽  
Aycha Sayeh ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Methylenetetrahydrofolate Reductase ◽  
A1298c Polymorphism
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