Viral Breakthrough Is Associated With Resistance Using Direct Acting Agents in Patients Treated for Chronic Hepatitis C Infection

2014 ◽  
Vol 48 (6) ◽  
pp. 548-552
Author(s):  
Kali Zhou ◽  
Jessica Ferguson ◽  
Sherona Bau ◽  
Sammy Saab
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Hepatitis C Infection ◽  
Viral Breakthrough ◽  
Direct Acting

scholarly journals A Viral Dynamic Model for Treatment Regimens with Direct-acting Antivirals for Chronic Hepatitis C Infection

2012 ◽  
Vol 8 (1) ◽  
pp. e1002339 ◽  
Author(s):  
Bambang S. Adiwijaya ◽  
Tara L. Kieffer ◽  
Joshua Henshaw ◽  
Karen Eisenhauer ◽  
Holly Kimko ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Dynamic Model ◽  
Chronic Hepatitis C ◽  
Direct Acting Antivirals ◽  
Hepatitis C Infection ◽  
Treatment Regimens ◽  
Viral Dynamic ◽  
Direct Acting

scholarly journals Novel emerging treatments for hepatitis C infection: a fast-moving pipeline

2017 ◽  
Vol 10 (2) ◽  
pp. 277-282 ◽  
Author(s):  
Ara A. Kardashian ◽  
Paul J. Pockros
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Medical Science ◽  
Pegylated Interferon ◽  
Hepatitis C Infection ◽  
Emerging Treatments ◽  
Low Toxicity ◽  
Direct Acting ◽  
Cure Rates

Advances in the treatment of chronic hepatitis C has been one of the pinnacles of medical science in the last 25 years. The age of direct-acting antivirals (DAAs) has led to cure rates >95% with shorter duration and low toxicity regimens, thus changing the landscape of the era of pegylated interferon and ribavirin (RBV). However, there remain some challenges with these therapies as there are multiple regimens available with a fair amount of sophistication required to administer them. Treatment continues to require knowledge of prior treatment status, viral genotype and fibrosis assessment, thus affording an opportunity for improvement in future regimens. This update reviews some upcoming therapies for the treatment of chronic hepatitis C.

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