scholarly journals Risk assessment of obstructive sleep apnea syndrome in pediatric patients with vitamin D deficiency

Medicine ◽  
2016 ◽  
Vol 95 (39) ◽  
pp. e4632 ◽  
Author(s):  
Gamze Ozgurhan ◽  
Aysel Vehapoglu ◽  
Oznur Vermezoglu ◽  
Rabia Nur Temiz ◽  
Asuman Guney ◽  
...  
Author(s):  
Banu Musaffa Salepçi ◽  
Benan Caglayan ◽  
Elif Torun Parmaksiz ◽  
Nesrin Kiral ◽  
Ali Fidan ◽  
...  

Endocrine ◽  
2013 ◽  
Vol 45 (2) ◽  
pp. 311-318 ◽  
Author(s):  
Ersin Sukru Erden ◽  
Sebahat Genc ◽  
Sedat Motor ◽  
Ihsan Ustun ◽  
Kemal Turker Ulutas ◽  
...  

Author(s):  
Hülya Albayrak ◽  
Nevin Fazlıoğlu ◽  
Bahadır Batar ◽  
Mehmet Emin Yanık ◽  
Mustafa Oran ◽  
...  

Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 174 ◽  
Author(s):  
Kostas Archontogeorgis ◽  
Nikolaos Papanas ◽  
Evangelos C. Rizos ◽  
Evangelia Nena ◽  
Athanasios Zissimopoulos ◽  
...  

Background and objectives: Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular and metabolic risk factors, such as insulin resistance. Furthermore, OSAS has been associated with decreased levels of vitamin D (Vit D). The aim of the study was to assess the association between Vit D levels (expressed as 25(OH)D serum levels) and insulin resistance in patients with OSAS. Materials and Methods: Serum 25(OH)D levels were measured in consecutive subjects who had undergone polysomnography and pulmonary function testing. OSAS patients were divided into those with (homeostatic model assessment [HOMA-IR] ≥ 2) and without insulin resistance (HOMA-IR < 2). Results: Overall, 92 patients (81 males) were included in the study. OSAS patients with insulin resistance significantly differed from those without insulin resistance in terms of the body-mass index (BMI) (36.3 ± 5.8 compared to 32 ± 5.6 kg/m2, respectively, p = 0.001), apnoea-hypopnoea index (AHI) (57.4 ± 28.9 compared to 40.9 ± 27.9 events/h, respectively, p = 0.009) and indices of hypoxia during sleep. Patients with OSAS and insulin resistance had lower levels of serum 25 (OH) D compared with OSAS but without insulin resistance (19.3 ± 11.5 vs 26.7 ± 12.2 ng/mL, respectively, p = 0.005). Regression analysis demonstrated a negative association of 25(OH)D levels (β = −0.048, odds ratio [OR]: 0.953, 95% confidence interval [CI]: 0.913–0.995, p = 0.030) and a positive association of BMI (β = 0.110, OR: 1.116, 95% CI: 1.007–1.237, p = 0.036) with insulin resistance. Conclusions: Vit D insufficiency was significantly more frequent among OSAS patients with insulin resistance. Both low 25(OH)D levels and high BMI were associated with the risk of insulin resistance in this population.


2018 ◽  
Vol 16 (4) ◽  
pp. 190-196 ◽  
Author(s):  
Kostas Archontogeorgis ◽  
Evangelia Nena ◽  
Nikolaos Papanas ◽  
Manfredi Rizzo ◽  
Athanasios Voulgaris ◽  
...  

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