scholarly journals HCV core antigen is a useful predictor during pegylated-interferon/ribavirin therapy in patients with hepatitis C virus genotype 1b

Medicine ◽  
2019 ◽  
Vol 98 (10) ◽  
pp. e14795
Author(s):  
Zhijuan Fan ◽  
Junfeng Liu ◽  
Fengmei Wang ◽  
Jingmin Liu ◽  
Xian Ding ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pegylated Interferon ◽  
Core Antigen ◽  
Virus Genotype ◽  
Hcv Core Antigen ◽  
Genotype 1B

scholarly journals Early viral kinetics and response to treatment in a hepatitis C virus genotype 5 infected patient

2011 ◽  
Vol 1 (2) ◽  
pp. 28
Author(s):  
Emanuele Durante-Mangoni ◽  
Domenico Iossa ◽  
Umberto Malgeri
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Treatment ◽  
Pegylated Interferon ◽  
Response To Treatment ◽  
Core Antigen ◽  
Hcv Rna ◽  
Virus Genotype ◽  
Viral Kinetics ◽  
Genotype 5

Genotype 5 hepatitis C has been poorly studied despite its worldwide spread. We have analyzed the early kinetics of genotype 5 hepatitis C virus RNA during pegylated interferon/ribavirin treatment in a 59-year-old man with active liver necroinflammatory changes and advanced liver fibrosis. The patient had a high viral load but a small serum level of hepatitis C core antigen. On combination antiviral treatment with pegylated-interferon alpha 2a, 180 ?g/week, and ribavirin, 1200 mg/day, the patient experienced an impressive reduction in serum HCV RNA as early as day 2 of treatment and eventually became a sustained virological responder. Our viral kinetics data support previous clinical studies showing HCV genotype 5 could be as intrinsically sensitive to interferon as HCV genotypes 2 and 3.

scholarly journals An Open Pilot Study Exploring the Efficacy of Fluvastatin, Pegylated Interferon and Ribavirin in Patients with Hepatitis C Virus Genotype 1b in High Viral Loads

Intervirology ◽  
2009 ◽  
Vol 52 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Hitomi Sezaki ◽  
Fumitaka Suzuki ◽  
Norio Akuta ◽  
Hiromi Yatsuji ◽  
Tetsuya Hosaka ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pilot Study ◽  
Pegylated Interferon ◽  
Virus Genotype ◽  
Viral Loads ◽  
Genotype 1B ◽  
Open Pilot

Sofosbuvir, pegylated interferon, and ribavirin for retreatment of hepatitis C virus genotype 1b following sofosbuvir and ledipasvir failure

Hepatology ◽  
2018 ◽  
Vol 67 (5) ◽  
pp. 2049-2050
Author(s):  
Chetan Kalal ◽  
Akash Shukla ◽  
Ravi Mohanka ◽  
Mihir Vora ◽  
Priyesh Patel ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pegylated Interferon ◽  
Virus Genotype ◽  
Genotype 1B
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