scholarly journals Prediction of in vitro fertilization outcome at different antral follicle count thresholds combined with female age, female cause of infertility, and ovarian response in a prospective cohort of 8269 women

Medicine ◽  
2019 ◽  
Vol 98 (41) ◽  
pp. e17470 ◽  
Author(s):  
ShuJie Liao ◽  
Jianwu Xiong ◽  
Haiting Tu ◽  
Cheng Hu ◽  
Wulin Pan ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Prospective Cohort ◽  
Ovarian Response ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Female Age ◽  
Vitro Fertilization

scholarly journals Effects of Hydrosalpinx on Endometrial Implantation Failures: Evaluating Salpingectomy in Women Undergoing in vitro fertilization

2021 ◽  
Author(s):  
Antonio Palagiano ◽  
Mauro Cozzolino ◽  
Filippo Maria Ubaldi ◽  
Chiara Palagiano ◽  
Maria Elisabetta Coccia
Keyword(s):  
In Vitro Fertilization ◽  
Oocyte Retrieval ◽  
Ovarian Response ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Endometrial Receptivity ◽  
Vitro Fertilization ◽  
Ovid Medline ◽  
Ultrasonographic Guidance

AbstractHydrosalpinx is a disease characterized by the obstruction of the salpinx, with progressive accumulation in the shape of a fluid-filled sac at the distal part of the tuba uterina, and closed to the ovary. Women with hydrosalpinges have lower implantation and pregnancy rates due to a combination of mechanical and chemical factors thought to disrupt the endometrial environment. Evidence suggests that the presence of hydrosalpinx reduces the rate of pregnancy with assisted reproductive technology. The main aim of the present is review to make an overview of the possible effects of hydrosalpinx on in vitro fertilization (IVF). We conducted a literature search on the PubMed, Ovid MEDLINE, and Google Scholar data bases regarding hydrosalpinx and IVF outcomes. Hydrosalpinx probably has a direct toxic effect on sperm motility and on the embryos. In addition, the increasing liquid inside the salpinges could alter the mechanisms of endometrial receptivity. The window of endometrial receptivity is essential in the implantation of blastocysts, and it triggers multiple reactions arising from the endometrium as well as the blastocysts. Hydrosalpinx could influence the expression of homeobox A10 (HOXA10) gene, which plays an essential role in directing embryonic development and implantation. Salpingectomy restores the endometrial expression of HOXA10; therefore, it may be one mechanism by which tubal removal could result in improved implantation rates in IVF. In addition, salpingectomy does not affect the ovarian response, nor reduces the antral follicle count. Further studies are needed to establish the therapeutic value of fluid aspiration under ultrasonographic guidance, during or after oocyte retrieval, in terms of pregnancy rate and ongoing pregnancy.

P–599 random antral follicle count, performed at any day of the menstrual cycle, demonstrates the same predictive value for ovarian response in in vitro fertilization cycles

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
M Razafintsalama ◽  
M Bah ◽  
G Amand ◽  
L Vienet-Lègue ◽  
C Pietin-Vialle ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
In Vitro Fertilization ◽  
Predictive Value ◽  
Ovarian Response ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Follicular Phase ◽  
Vitro Fertilization ◽  
Early Follicular Phase

Abstract Study question Does antral follicle count (AFC) retains its predictive value for ovarian response to stimulation for in vitro fertilization (IVF) throughout the whole menstrual cycle? Summary answer AFC is strongly correlated to anti-mullerian hormone (AMH) and highly predictive of good ovarian response whatever the day of cycle the ultrasound is performed. What is known already Usually performed in the early follicular phase (at day 2–3 of the menstrual cycle), AFC and AMH are the most accurate markers of ovarian reserve. They are routinely used to predict ovarian response to ovarian stimulation for IVF and eventually to individualize the gonadotropin starting dose. Study design, size, duration Retrospective cohort study performed between January, 2017 and December, 2019. Participants/materials, setting, methods 410 consecutive women aged 20 to 42 years were included. Random AFC (r-AFC) was performed during the fertility workup whatever the day of their menstrual cycle was: early follicular phase i.e. day 1 to day 6 (eFP-AFC), mid follicular phase i.e. day 7 to 12 (mFP-AFC) and luteal phase i.e. day 13 or after (LP-AFC). A second AFC was performed before the start of the stimulation (SD1-AFC). AMH was measured in the early follicular phase. Main results and the role of chance Random AFC (r-AFC) was correlated to AMH (r = 0.692; p < 0.001), SD1-AFC (r = 0.756; p < 0.001) and number of oocytes retrieved (r = 0.491; p < 0.001). When regarding AFC depending on the cycle day group, the correlation with AMH was significantly higher for the LP-AFC, (LP-AFC) (r = 0.853) than for the eFP-AFC (r = 0.657; p < 0.001) and for the mFP-AFC (r = 0.668). The correlation with SD1-AFC was similar regardless of the time of performance of r-AFC (r = 0.739, 0.783, 0.733, respectively for eFP, mFP and LP-AFC). Moreover, the ROC analysis showed the same predictive value for good ovarian response (more than 6 oocytes retrieved) for the eFP-AFC, mFP-AFC and LP-AFC (AUC 0.73, 0.75 and 0.84 respectively) as well as for AMH and SD1-AFC (AUC 0.74 and 0.74, respectively). Limitations, reasons for caution This is a retrospective analysis, however data were prospectively collected and the method for ultrasound acquisition of AFC was standardized. Wider implications of the findings: The absence of significant variation of AFC across the menstrual cycle allows to its random performance. Ultrasound performed besides early follicular phase discloses informations on ovaries, the uterus and the endometrium. It is more comfortable and convenient for women and physicians by limiting targeted appointment during menstruation and reiterated examination. Trial registration number Not applicable

Prediction of in vitro fertilization outcome at different antral follicle count thresholds in a prospective cohort of 1,012 women

2012 ◽  
Vol 98 (3) ◽  
pp. 657-663 ◽  
Author(s):  
Kannamannadiar Jayaprakasan ◽  
YeeYin Chan ◽  
Rumana Islam ◽  
Zeina Haoula ◽  
James Hopkisson ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Prospective Cohort ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Vitro Fertilization

scholarly journals Measurement of antral follicle count in patients undergoing in vitro fertilization treatment: results of a worldwide web-based survey

2015 ◽  
Vol 32 (10) ◽  
pp. 1435-1440 ◽  
Author(s):  
Mindy S. Christianson ◽  
Gon Shoham ◽  
Kyle J. Tobler ◽  
Yulian Zhao ◽  
Christina N. Cordeiro ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Treatment Results ◽  
Web Based ◽  
Vitro Fertilization ◽  
Worldwide Web
Sign in / Sign up

Export Citation Format

Share Document