Idiopathic pulmonary arterial hypertension associated with a novel frameshift mutation in the bone morphogenetic protein receptor II gene and enhanced bone morphogenetic protein signaling

Frameshift Mutation ◽

Protein Signaling ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Prevalence and clinical features of bone morphogenetic protein receptor type 2 mutation in Korean idiopathic pulmonary arterial hypertension patients: The PILGRIM explorative cohort

PLoS ONE ◽

10.1371/journal.pone.0238698 ◽

2020 ◽

Vol 15 (9) ◽

pp. e0238698

Author(s):

Albert Youngwoo Jang ◽

Bo-Gyeong Kim ◽

Sunkoo Kwon ◽

Jiyoung Seo ◽

Hyung Kwan Kim ◽

...

Keyword(s):

Arterial Hypertension ◽

Clinical Features ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension

American Journal of Respiratory Cell and Molecular Biology ◽

10.1165/rcmb.2015-0402oc ◽

2016 ◽

Vol 55 (4) ◽

pp. 564-575 ◽

Cited By ~ 13

Author(s):

Jarrod W. Barnes ◽

Elif T. Kucera ◽

Liping Tian ◽

Noël E. Mellor ◽

Nina Dvorina ◽

...

Keyword(s):

Arterial Hypertension ◽

Bone Morphogenic Protein ◽

Protein Signaling ◽

Morphogenetic Protein ◽

Bone Morphogenetic Protein Receptor 2 Mutations in Adults and Children With Idiopathic Pulmonary Arterial Hypertension

CHEST Journal ◽

10.1378/chest.128.6_suppl.618s ◽

2005 ◽

Vol 128 (6) ◽

pp. 618S ◽

Cited By ~ 13

Author(s):

Kari E. Roberts ◽

Robyn J. Barst ◽

Jude J. McElroy ◽

Allison Widlitz ◽

Kiran Chada ◽

...

Keyword(s):

Arterial Hypertension ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Adults And Children ◽

Mutations in the Gene Encoding Bone Morphogenetic Protein Receptor 2 in Patients With Idiopathic Pulmonary Arterial Hypertension

Archivos de Bronconeumología (English Edition) ◽

10.1016/s1579-2129(08)60006-3 ◽

2008 ◽

Vol 44 (1) ◽

pp. 29-34 ◽

Cited By ~ 1

Author(s):

Adolfo Baloira ◽

Carlos Vilariño ◽

Virginia Leiro ◽

Diana Valverde

Keyword(s):

Arterial Hypertension ◽

Gene Encoding ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Bone Morphogenetic Protein Signaling in Familial Versus Idiopathic Pulmonary Arterial Hypertension.

10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a6008 ◽

2009 ◽

Author(s):

L Dewachter ◽

S Adnot ◽

C Guignabert ◽

L Tu ◽

E Marcos ◽

...

Keyword(s):

Arterial Hypertension ◽

Protein Signaling ◽

Morphogenetic Protein ◽

Faculty Opinions recommendation of Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726360855.793519766 ◽

2016 ◽

Author(s):

Vinicio de Jesus Perez

Keyword(s):

Arterial Hypertension ◽

Bone Morphogenic Protein ◽

Protein Signaling ◽

Morphogenetic Protein ◽

Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue

Human Molecular Genetics ◽

10.1093/hmg/ddn214 ◽

2008 ◽

Vol 17 (20) ◽

pp. 3180-3190 ◽

Cited By ~ 57

Author(s):

A. Sobolewski ◽

N. Rudarakanchana ◽

P. D. Upton ◽

J. Yang ◽

T. K. Crilley ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Trafficking ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.107.141200 ◽

2007 ◽

Vol 27 (5) ◽

pp. 1072-1078 ◽

Cited By ~ 97

Author(s):

Rory E. Morty ◽

Bozena Nejman ◽

Grazyna Kwapiszewska ◽

Matthias Hecker ◽

Anka Zakrzewicz ◽

...

Keyword(s):

Arterial Hypertension ◽

Protein Signaling ◽

Morphogenetic Protein ◽

In Vivo Interactions With Serotonin And Bone Morphogenetic Protein Receptor 2 Deficiency In The Development Of Pulmonary Arterial Hypertension

10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6312 ◽

2010 ◽

Author(s):

Neil A. MacRitchie ◽

Yvonne Dempsie ◽

Margaret Nilsen ◽

Nicholas W. Morrell ◽

Margaret R. MacLean

Keyword(s):

Arterial Hypertension ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Bone Morphogenetic Protein Receptor 2 Mutations Impair T Regulatory Cell Function and Promote Inflammation in Pulmonary Arterial Hypertension

10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2682 ◽

2020 ◽

Author(s):

G. Peng ◽

A. Tian ◽

T. Guan ◽

T.H. Wu ◽

M.R. Nicolls

Keyword(s):

Arterial Hypertension ◽

Cell Function ◽

T Regulatory Cell ◽

Regulatory Cell ◽

Protein Receptor ◽

Morphogenetic Protein ◽