scholarly journals Open abdomen treatment for complicated intra-abdominal infection patients with gastrointestinal fistula can reduce the mortality

Medicine ◽  
2020 ◽  
Vol 99 (16) ◽  
pp. e19692
Author(s):  
Xuzhao Li ◽  
Jiangpeng Wei ◽  
Ying Zhang ◽  
Weizhong Wang ◽  
Guosheng Wu ◽  
...  
Keyword(s):  
Open Abdomen ◽  
Gastrointestinal Fistula ◽  
Abdominal Infection ◽  
Intra Abdominal Infection

Open Abdomen Treatment for Septic Patients with Gastrointestinal Fistula: From Fistula Control to Definitive Closure

2014 ◽  
Vol 80 (4) ◽  
pp. 339-347 ◽  
Author(s):  
Jianan Ren ◽  
Yujie Yuan ◽  
Yunzhao Zhao ◽  
Guosheng Gu ◽  
Gefei Wang ◽  
...  
Keyword(s):  
Open Abdomen ◽  
Abdominal Wall Reconstruction ◽  
Fascial Closure ◽  
Wound Complications ◽  
Temporary Abdominal Closure ◽  
Gastrointestinal Fistula ◽  
Operative Strategy ◽  
Abdominal Infection ◽  
Abdominal Closure ◽  
Intra Abdominal Infection

The use of open abdomen in the management of gastrointestinal fistula complicated with severe intra-abdominal infection is uncommon. This study was designed to evaluate outcomes of our staged approach for the infected open abdomen. Patients who had gastrointestinal fistula and underwent open abdomen treatment were retrospectively reviewed. Various materials such as polypropylene mesh and a modified sandwich package were used to achieve temporary abdominal closure followed by skin grafting when the granulation bed matured. A delayed definitive operation was performed for final abdominal closure without implant of prosthetic mesh. Between 1999 and 2009, 56 (68.3%) of 82 patients survived through this treatment. Among them, 42 patients achieved final abdominal closure. Spontaneous fistula closure occurred in 16 patients with secondary fistula recorded in six patients. Besides, wound complications occurred in 13 patients with two cases for pulmonary infection. Within a 12-month follow-up period after definitive closure, no additional fistula was recorded excluding planned ventral hernia repair. Open abdomen treatment was effective for gastrointestinal fistula complicated by severe intra-abdominal infection. A delayed and deliberate operative strategy aiming at fistula excision and fascial closure, with simultaneous abdominal wall reconstruction, was required for the infected open abdomen.

scholarly journals Current Status of the Open Abdomen Treatment for Intra-Abdominal Infection

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Yujie Yuan ◽  
Jianan Ren ◽  
Yulong He
Keyword(s):  
Open Abdomen ◽  
Damage Control ◽  
Fluid Management ◽  
Damage Control Surgery ◽  
Skin Grafting ◽  
Current Status ◽  
Fascial Closure ◽  
Surgical Interventions ◽  
Abdominal Infection ◽  
Intra Abdominal Infection

The open abdomen has become an important approach for critically ill patients who require emergent abdominal surgical interventions. This treatment, originating from the concept of damage control surgery, was first applied in severe traumatic patients. The ultimate goal is to achieve formal abdominal fascial closure by several attempts and adjuvant therapies (fluid management, nutritional support, skin grafting, etc.). Up to the present, open abdomen therapy becomes matured and is multistage-approached in the management of patients with severe trauma. However, its application in patients with intra-abdominal infection still presents great challenges due to critical complications and poor clinical outcomes. This review focuses on the specific use of the open abdomen in such populations and detailedly introduces current concerns and advanced progress about this therapy.

Postoperative intra-abdominal infection increases angiogenesis and tumor recurrence after surgical excision of colon cancer in mice

Surgery ◽  
2010 ◽  
Vol 147 (1) ◽  
pp. 120-126 ◽  
Author(s):  
Bernhard Bohle ◽  
Miguel Pera ◽  
Marta Pascual ◽  
Sandra Alonso ◽  
Xavier Mayol ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Tumor Recurrence ◽  
Surgical Excision ◽  
Abdominal Infection ◽  
Intra Abdominal Infection

Clinical Practice Guidelines in Complicated Intra-Abdominal Infection 2018: An Indonesian Perspective

2019 ◽  
Vol 20 (1) ◽  
pp. 83-90 ◽  
Author(s):  
Toar J.M. Lalisang ◽  
Nurhayat Usman ◽  
Iswanto Hendrawidjaya ◽  
Adeodatus Y. Handaya ◽  
Safruddin Nasution ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Abdominal Infection ◽  
Intra Abdominal Infection
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