scholarly journals A novel algorithm to predict oxygen desaturation in sedated patients with obstructive sleep apnea utilizing polysomnography

Medicine ◽  
2020 ◽  
Vol 99 (34) ◽  
pp. e21915
Author(s):  
Min-Hsien Chiang ◽  
Sheng-Dean Luo ◽  
Hsin-Ching Lin ◽  
Shao-Yun Hou ◽  
Ting-Yu Ke ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Oxygen Desaturation ◽  
Obstructive Sleep ◽  
Novel Algorithm

scholarly journals 0610 Prevalence of Positional Obstructive Sleep Apnea Based on 3% Vs 4% Oxygen Desaturation Using Home Sleep Apnea Testing

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A233-A234
Author(s):  
M Mandal ◽  
R Rengan ◽  
S Rani ◽  
J Ramzy ◽  
M Vega Sanchez ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Oxygen Desaturation ◽  
Apnea Hypopnea Index ◽  
Apnea Test ◽  
Positional Obstructive Sleep Apnea ◽  
Obstructive Sleep ◽  
Respiratory Event ◽  
Home Sleep Apnea Testing ◽  
Definition Of

Abstract Introduction Approximately 30% of patient with obstructive sleep apnea (OSA) have positional OSA [non-supine apnea-hypopnea index (AHI) < 5 events/hr]. However, the prevalence is based on variable definitions for hypopneas related to the degree of oxygen desaturation. In addition, use of a home sleep apnea test (HSAT) to identify positional OSA is limited. We hypothesized that in patients evaluated with an HSAT, using a definition for hypopneas based on 4% compared to 3% oxygen desaturation will significantly decrease the percentage diagnosed with positional OSA. Methods Fourteen patients with positional OSA based on a non-supine respiratory event index (REI) < 5 events/hr were included. The initial diagnosis was determined based on a hypopnea definition of ≥ 3% oxygen desaturation. The studies were reanalyzed using a hypopnea definition of ≥ 4% oxygen desaturation. Results Fourteen patients [9 (64%) males, 46±14 yrs, BMI 31±6 kg/m2, ESS 7±5, REI 9±3 events/hr, mean SaO2 94±2%, lowest SaO2 81±6%, %TST SaO2 < 90% 4±6%] were identified with positional OSA (supine REI 16±7 events/hr, non-supine REI 3±1 events/hr) using a hypopneas definition of ≥ 3% oxygen desaturation. When reanalyzed using a hypopnea ≥ 4% oxygen desaturation there was a significant decrease in the REI to 7±2 events/hr (p<0.001). Three patients (21%) no longer were considered to have OSA. These patients were younger (32±14 vs. 50±11yrs, p=0.03) and had less severe OSA (REI 6±1 vs. 9±3 events/hr (p=0.04), but there was no difference in BMI (32±11 vs. 31±5 kg/m2, p=0.9) or mean and lowest SaO2 (96±0.4 vs. 94±2%, p=0.13, and 82±8 vs. 81±6%, p=0.9, respectively). Conclusion In patients with mild positional OSA, using a hypopnea definition of at least 4% vs. 3% oxygen desaturation on a HSAT will have a significant effect on the overall REI and often exclude patients who would otherwise be treated for OSA. Support None.

scholarly journals Critical Oxygen Desaturation from Obstructive Sleep Apnea

2014 ◽  
Vol 11 (2) ◽  
pp. 66-68
Author(s):  
Doh-Eui Kim ◽  
Kwang Ik Yang ◽  
Saeromi Kim ◽  
Hyung Geun Oh ◽  
Du Shin Jeong ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Oxygen Desaturation ◽  
Obstructive Sleep ◽  
Critical Oxygen

scholarly journals Long-term All-Cause Mortality Risk in Obstructive Sleep Apnea Using Hypopneas Defined by a ≥3 Percent Oxygen Desaturation or Arousal

2021 ◽  
Vol 23 (1) ◽  
pp. 23-35
Author(s):  
Rohit Budhiraja ◽  
◽  
Stuart Quan
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Mortality Risk ◽  
Oxygen Desaturation ◽  
Risk Of Death ◽  
Obstructive Sleep ◽  
All Cause Mortality ◽  
Categorical Models

Study Objectives: Some prior studies have demonstrated an increase in mortality associated with obstructive sleep apnea (OSA) utilizing a definition of OSA that requires a minimum 4% oxygen desaturation to identify a hypopnea. No large community-based studies have determined the risk of long-term mortality with OSA with hypopneas defined by a ≥3% O2 desaturation or arousal (AHI3%A). Methods: Data from 5591 Sleep Heart Health Study participants without prevalent cardiovascular disease at baseline who underwent polysomnography were analyzed regarding OSA diagnosed using the AHI3%A criteria and all-cause mortality over a mean follow up period of 10.9±3.2 years. Results: There were 1050 deaths in this group during the follow-up period. A Kaplan-Meir plot of survival revealed a reduction in survival with increasing AHI severity. Cox proportional hazards regression models revealed significantly increased all-cause mortality risk with increasing AHI, hazard ratio (HR, 95% CI) 1.13 (1.04-1.23), after adjusting for age, sex, race, BMI, cholesterol, HDL, self-reported hypertension and/or diabetes and smoking status. In categorical models, the mortality risk was significantly higher with severe OSA [adjusted HR 1.38 (1.09-1.76)]. When stratified by gender or age, severe OSA was associated with increased risk of death in men [adjusted HR 1.14 (1.01-1.28)] and in those <70 years of age [adjusted HR 1.51 (1.02-2.26)]. In contrast, AHI severity was not associated with increased mortality in women or those ≥70 years of age in fully adjusted models. Conclusion: Severe AHI3%A OSA is associated with significantly increased mortality risk, especially in men and those <70 years of age.

scholarly journals Oxygen Desaturation Index calculation: impact of different methodologies

2021 ◽  
Author(s):  
Diego Munduruca Domingues ◽  
Filipe Vilela Soares ◽  
Geraldo Lorenzi-Filho ◽  
Henrique Takachi Moriya
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Obstruction ◽  
Oxygen Desaturation ◽  
Desaturation Index ◽  
Oxygen Desaturation Index ◽  
Obstructive Sleep ◽  
Variable Performance ◽  
Index Calculation

Obstructive Sleep Apnea (OSA) is a syndrome characterized by episodes of airway obstruction, which causes oxygen desaturation events. These events can be identified by oximetry analysis and are used as one of the parameters to diagnose OSA. However, desaturation events have an inaccurate definition in manuals and in most of the literature. Thus, this work aims to evaluate whether different methodologies for the calculation of desaturation events impact the Oxygen Desaturation Index (ODI) and the diagnosis of OSA. The results indicated that the ODI values are significantly different from each other (p <0.001) and the methodologies provided variable performance for the diagnosis of OSA.

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