scholarly journals Study on the preventive effect of ramelteon on the onset of sleep disorder after general anesthesia in patients with autism spectrum disorder

Medicine ◽  
2020 ◽  
Vol 99 (43) ◽  
pp. e22826
Author(s):  
Terumi Ayuse ◽  
Yu Ozaki-Honda ◽  
Shinji Kurata ◽  
Gaku Mishima ◽  
Kensuke Kiriishi ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
General Anesthesia ◽  
Sleep Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Preventive Effect

Gastrointestinal dysfunctions as a risk factor for sleep disorders in children with idiopathic autism spectrum disorder: A retrospective cohort study

Autism ◽  
2017 ◽  
Vol 21 (8) ◽  
pp. 1010-1020 ◽  
Author(s):  
Lena M McCue ◽  
Louise H Flick ◽  
Kimberly A Twyman ◽  
Hong Xian
Keyword(s):  
Quality Of Life ◽  
Autism Spectrum Disorder ◽  
Confidence Interval ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Behavioral Problems ◽  
Sleep Problems ◽  
Autism Spectrum ◽  
Spectrum Disorder

Sleep disorders often co-occur with autism spectrum disorder. They further exacerbate autism spectrum disorder symptoms and interfere with children’s and parental quality of life. This study examines whether gastrointestinal dysfunctions increase the odds of having sleep disorders in 610 children with idiopathic autism spectrum disorder, aged 2–18 years, from the Autism Genetic Resource Exchange research program. The adjusted odds ratio for sleep disorder among those with gastrointestinal dysfunctions compared to those without was 1.74 (95% confidence interval: 1.22–2.48). In addition, the odds of having multiple sleep disorder symptoms among children with gastrointestinal dysfunctions, adjusted for age, gender, behavioral problems, bed wetting, current and past supplements, and current and past medications for autism spectrum disorder symptoms were 1.75 (95% confidence interval: 1.10–2.79) compared to children without gastrointestinal dysfunctions. Early detection and treatment of gastrointestinal dysfunctions in autism spectrum disorder may be means to reduce prevalence and severity of sleep problems and improve quality of life and developmental outcomes in this population.

Exposure to General Anesthesia May Contribute to the Association between Cesarean Delivery and Autism Spectrum Disorder

2019 ◽  
Vol 49 (8) ◽  
pp. 3127-3135 ◽  
Author(s):  
Maayan Huberman Samuel ◽  
Gal Meiri ◽  
Ilan Dinstein ◽  
Hagit Flusser ◽  
Analiya Michaelovski ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
General Anesthesia ◽  
Cesarean Delivery ◽  
Autism Spectrum ◽  
Spectrum Disorder

Association Between Exposure of Children to General Anesthesia and Autism Spectrum Disorder

2021 ◽  
Author(s):  
Mariana L. Laporta ◽  
Juraj Sprung ◽  
Caroline A. Fejedelem ◽  
Dustin T. Henning ◽  
Amy L. Weaver ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
General Anesthesia ◽  
Autism Spectrum ◽  
Spectrum Disorder

scholarly journals Dental care for children with autism spectrum disorder

2018 ◽  
Vol 50 (3) ◽  
pp. 160
Author(s):  
Amrita Widyagarini ◽  
Margaretha Suharsini
Keyword(s):  
Autism Spectrum Disorder ◽  
Case Management ◽  
General Anesthesia ◽  
Dental Care ◽  
Dental Treatment ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Behavioral Observations ◽  
Treatment Plans

Background: Providing dental treatment for children with autism spectrum disorder (ASD) represents a challenge for dentists. In the dental care of such children, the treatment plans implemented are usually determined by several factors, including: the type of autism spectrum disorder, the degree of patient cooperation, dentist/patient communication, the required treatment, self-care skills and parental/dentist support. Purpose: The purpose of this case report was to report the dental care delivered in the cases of two pediatric patients with ASD. Case 1: A 10.7 year-old boy with a nonverbal form of ASD who was experiencing recurrent pain in his lower left posterior tooth and also presented a blackened tooth. Case 2: A 9.6 year-old boy with a nonverbal form of ASD suffering from numerous painful cavities. Case management 1: On the day of the first visit, the boy was the subject of several behavioral observations. During the day of the second visit, he underwent a brief intraoral examination at a dental unit in order to arrive at a temporary diagnosis before appropriate was decided upon treatment in consultation with his parents. The implemented treatment plans comprised dental extraction and preventive restoration under general anesthesia. Case management 2: On the first visit, the boy underwent behavioral observations followed by early intraoral examination involving physical restraint approach. During the second visit, several treatment plans such as: general anesthesia, tooth extraction, restoration, and pulp-capping treatment were formulated. Conclusion: It can be concluded that general anesthesia was considered an appropriate dental treatment plan since the two patients in question were extremely co-operative during the necessary procedures. In other words, pediatric dental care treatment plans in cases of ASD should be determined by clearly-defined criteria, specifically the benefits and risks of the treatment plans for the safety of both patient and dental care team.

Employment status is related to sleep problems in adults with autism spectrum disorder and no comorbid intellectual impairment

Autism ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 531-536 ◽  
Author(s):  
Emma K Baker ◽  
Amanda L Richdale ◽  
Agnes Hazi
Keyword(s):  
Autism Spectrum Disorder ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Sleep Problems ◽  
Autism Spectrum ◽  
International Classification ◽  
Spectrum Disorder ◽  
Adults With Autism ◽  
Study Participants

Both sleep problems and unemployment are common in adults with autism spectrum disorder; however, little research has explored this relationship in this population. This study aimed to explore factors that may be associated with the presence of an International Classification of Sleep Disorders–Third Edition defined sleep disorder in adults with autism spectrum disorder (IQ > 80). A total of 36 adults with autism spectrum disorder and 36 controls were included in the study. Participants completed a 14-day actigraphy assessment and questionnaire battery. Overall, 20 adults with autism spectrum disorder met the International Classification of Sleep Disorders–Third Edition criteria for insomnia and/or a circadian rhythm sleep-wake disorder, while only 4 controls met criteria for these disorders. Adults with autism spectrum disorder and an International Classification of Sleep Disorders–Third Edition sleep disorder had higher scores on the Pittsburgh Sleep Quality Index and were more likely to be unemployed compared to adults with autism spectrum disorder and no sleep disorder. The findings demonstrate, for the first time, that sleep problems are associated with unemployment in adults with autism spectrum disorder. Further research exploring the direction of this effect is required; sleep problems that have developed during adolescence make attainment of employment for those with autism spectrum disorder difficult, or unemployment results in less restrictions required for optimal and appropriate sleep timing.

Development of Neural Structure and Function in Autism Spectrum Disorder: Potential Implications for Learning Language

2020 ◽  
Vol 29 (4) ◽  
pp. 1783-1797
Author(s):  
Kelly L. Coburn ◽  
Diane L. Williams
Keyword(s):  
Autism Spectrum Disorder ◽  
Language Development ◽  
Diffusion Tensor ◽  
Autism Spectrum ◽  
Language Intervention ◽  
Spectrum Disorder ◽  
Autistic Children ◽  
Neural Structure ◽  
Complex Information ◽  
And Function

Purpose Neurodevelopmental processes that begin during gestation and continue throughout childhood typically support language development. Understanding these processes can help us to understand the disruptions to language that occur in neurodevelopmental conditions, such as autism spectrum disorder (ASD). Method For this tutorial, we conducted a focused literature review on typical postnatal brain development and structural and functional magnetic resonance imaging, diffusion tensor imaging, magnetoencephalography, and electroencephalography studies of the neurodevelopmental differences that occur in ASD. We then integrated this knowledge with the literature on evidence-based speech-language intervention practices for autistic children. Results In ASD, structural differences include altered patterns of cortical growth and myelination. Functional differences occur at all brain levels, from lateralization of cortical functions to the rhythmic activations of single neurons. Neuronal oscillations, in particular, could help explain disrupted language development by elucidating the timing differences that contribute to altered functional connectivity, complex information processing, and speech parsing. Findings related to implicit statistical learning, explicit task learning, multisensory integration, and reinforcement in ASD are also discussed. Conclusions Consideration of the neural differences in autistic children provides additional scientific support for current recommended language intervention practices. Recommendations consistent with these neurological findings include the use of short, simple utterances; repetition of syntactic structures using varied vocabulary; pause time; visual supports; and individualized sensory modifications.

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