Differentiated CaCo-2 cells as an in-vitro model to evaluate de-novo apolipoprotein A-I production in the small intestine

2009 ◽  
Vol 21 (6) ◽  
pp. 642-649 ◽  
Author(s):  
Stefan P.J. Dullens ◽  
Ronald P. Mensink ◽  
Edwin C.M. Mariman ◽  
Jogchum Plat
Keyword(s):  
Small Intestine ◽  
In Vitro Model ◽  
De Novo ◽  
Apolipoprotein A ◽  
Vitro Model

scholarly journals Silicon dioxide nanoparticle exposure affects small intestine function in an in vitro model

2018 ◽  
Vol 12 (5) ◽  
pp. 485-508 ◽  
Author(s):  
Zhongyuan Guo ◽  
Nicole J. Martucci ◽  
Yizhong Liu ◽  
Eusoo Yoo ◽  
Elad Tako ◽  
...  
Keyword(s):  
Small Intestine ◽  
Silicon Dioxide ◽  
In Vitro Model ◽  
Nanoparticle Exposure ◽  
Vitro Model ◽  
Silicon Dioxide Nanoparticle

scholarly journals Apolipoprotein A-I coating of protamine–oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood–brain barrier

2007 ◽  
Vol 117 (3) ◽  
pp. 301-311 ◽  
Author(s):  
Ingrid Kratzer ◽  
Karin Wernig ◽  
Ute Panzenboeck ◽  
Eva Bernhart ◽  
Helga Reicher ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Particle Uptake ◽  
Apolipoprotein A ◽  
Blood Brain ◽  
Vitro Model

Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine

2010 ◽  
Vol 1 (1) ◽  
pp. 31-36 ◽  
Author(s):  
A. Maathuis ◽  
D. Keller ◽  
S. Farmer
Keyword(s):  
Small Intestine ◽  
Milk Protein ◽  
Intestinal Tract ◽  
In Vitro Model ◽  
Bacillus Coagulans ◽  
Protein Digestion ◽  
Vitro Model ◽  
Gastro Intestinal Tract ◽  
Carbohydrate Digestion

We have investigated the survival and activity of GanedenBC30 during passage through the upper gastro-intestinal tract. GanedenBC30 was tested in a dynamic, validated, in vitro model of the stomach and small intestine (TIM-1) on survival and its potential to aid in digestion of milk protein, lactose and fructose. The survival of GanedenBC30 was high (70%), although germination of the spores was minimal (<10%) under the conditions tested. Survival of the strain in the presence of lactose and fructose was markedly lower (56-59%) than in the absence of the sugars. The amount of digested milk protein available for absorption was somewhat higher (+0.2 g) when GanedenBC30 was added to the milk. When GanedenBC30 was tested with lactose or fructose added to the meal, the cumulative amount of lactate produced was slightly higher (+0.12-0.18 mmol) compared to the GanedenBC30 alone. In conclusion, although the differences in survival of GanedenBC30 are small, these results show the potential of GanedenBC30 to aid in protein digestion and in the digestion of lactose and fructose. If a larger fraction of the Bacillus coagulans cells had germinated, the influence on protein and carbohydrate digestion would probably have been much greater. Importance of the findings: the potential of GanedenBC30 to aid in the digestion of lactose and fructose could be used to prevent occurrence of intestinal symptoms in individuals sensitive to these carbohydrates.

Development of an Advanced Primary Human In Vitro Model of the Small Intestine

2016 ◽  
Vol 22 (9) ◽  
pp. 873-883 ◽  
Author(s):  
Matthias Schweinlin ◽  
Sabine Wilhelm ◽  
Ivo Schwedhelm ◽  
Jan Hansmann ◽  
Rene Rietscher ◽  
...  
Keyword(s):  
Small Intestine ◽  
In Vitro Model ◽  
Vitro Model

OS041. Apolipoprotein A-I protects normal integration of the trophoblast into endothelial cellular networks in an in vitro model of preeclampsia

2012 ◽  
Vol 2 (3) ◽  
pp. 198-199
Author(s):  
F. Charlton ◽  
B. Xu ◽  
A. Makris ◽  
A. Hennessy ◽  
K.-A. Rye
Keyword(s):  
Cellular Networks ◽  
In Vitro Model ◽  
Apolipoprotein A ◽  
Vitro Model

Characterization of the Maturation of Human Pro-apolipoprotein A-I in an in Vitro Model†

Biochemistry ◽  
2001 ◽  
Vol 40 (10) ◽  
pp. 3101-3108 ◽  
Author(s):  
Louise E. Pyle ◽  
Dmitri Sviridov ◽  
Noel H. Fidge
Keyword(s):  
In Vitro Model ◽  
Apolipoprotein A ◽  
Vitro Model
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