:
Colorectal cancer represents the third most frequently occurring cancer worldwide. In the
last decade, the survival of patients affected by metastatic colorectal cancer (mCRC) has improved
through the introduction of biological drugs. However, in this new and dynamic therapeutic context,
research about prognostic and predictive factors is important to guide the oncologists to effective
therapies as well as to improve the understanding of colorectal cancer biology. Their identification is
an intensive area of research and our future goal will be to depict tumour-specific "molecular signatures"
in order to predict the clinical course of the disease and the best treatments.
:
In this report, we describe clinical, pathological and molecular biomarkers that can play a role as
prognostic or predictive factors in mCRC.
Distinct Molecular Signatures of Aging in Healthy and HIV-Infected Individuals
