High Rates of Survival, Immune Reconstitution, and Virologic Suppression on Second-Line Antiretroviral Therapy in South Africa

2010 ◽  
Vol 53 (4) ◽  
pp. 500-506 ◽  
Author(s):  
Matthew P Fox ◽  
Prudence Ive ◽  
Lawrence Long ◽  
Mhairi Maskew ◽  
Ian Sanne
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Virologic Suppression ◽  
Second Line ◽  
Second Line Antiretroviral Therapy

Intensive adherence counselling for HIV-infected individuals failing second-line antiretroviral therapy in Johannesburg, South Africa

2016 ◽  
Vol 21 (9) ◽  
pp. 1131-1137 ◽  
Author(s):  
Matthew P. Fox ◽  
Rebecca Berhanu ◽  
Kim Steegen ◽  
Cindy Firnhaber ◽  
Prudence Ive ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Second Line ◽  
Adherence Counselling ◽  
Second Line Antiretroviral Therapy

scholarly journals Estimated use of abacavir among adults and children enrolled in public sector antiretroviral therapy programmes in Gauteng, South Africa

2012 ◽  
Vol 13 (3) ◽  
pp. 134-137 ◽  
Author(s):  
D Evans ◽  
M Maskwe ◽  
C Heneger ◽  
I Sanne
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Public Sector ◽  
Treatment Guidelines ◽  
Hiv Positive ◽  
Second Line ◽  
Gauteng Province ◽  
Paediatric Patients ◽  
Adults And Children ◽  
Second Line Antiretroviral Therapy

In South Africa, abacavir (ABC) is currently recommended as part of first- and second-line antiretroviral therapy (ART) for HIV-positive paediatric patients. Concerns about overprescribing of the drug, particularly to adults, led to an analysis of ABC use in public sector ART programmes. We investigated current prescription of the drug to adults and children accessing ART in 4 public sector programmes across Gauteng Province, South Africa. ABC was almost exclusively prescribed to children initiating ART and adults requiring regimen changes due to drug toxicities. Patterns of ABC use among HIV-positive paediatric patients followed national ART treatment guidelines on the application of the drug. Although ABC is commonly used in the private sector for adults, the current national ART treatment guidelines for adults and adolescents should include ABC as an alternative to standard first- or second-line ART.

scholarly journals Virologic Failure of Protease Inhibitor-Based Second-Line Antiretroviral Therapy without Resistance in a Large HIV Treatment Program in South Africa

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e32144 ◽  
Author(s):  
Julie H. Levison ◽  
Catherine Orrell ◽  
Sébastien Gallien ◽  
Daniel R. Kuritzkes ◽  
Naishin Fu ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Protease Inhibitor ◽  
Treatment Program ◽  
Virologic Failure ◽  
Hiv Treatment ◽  
Second Line ◽  
Second Line Antiretroviral Therapy

The high cost of second-line antiretroviral therapy for HIV/AIDS in South Africa

AIDS ◽  
2010 ◽  
Vol 24 (6) ◽  
pp. 915-919 ◽  
Author(s):  
Lawrence Long ◽  
Matthew Fox ◽  
Ian Sanne ◽  
Sydney Rosen
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Second Line ◽  
Second Line Antiretroviral Therapy ◽  
Hiv Aids

scholarly journals Adverse Drug Reactions Among Patients Initiating Second-Line Antiretroviral Therapy in South Africa

Drug Safety ◽  
2018 ◽  
Vol 41 (12) ◽  
pp. 1343-1353 ◽  
Author(s):  
Dorina Onoya ◽  
Kamban Hirasen ◽  
Liudmyla van den Berg ◽  
Jacqui Miot ◽  
Lawrence C. Long ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Adverse Drug Reactions ◽  
Second Line ◽  
Drug Reactions ◽  
Second Line Antiretroviral Therapy

scholarly journals Increased Mortality With Delayed and Missed Switch to Second-Line Antiretroviral Therapy in South Africa

2020 ◽  
Vol 84 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Helen Bell Gorrod ◽  
Richard Court ◽  
Michael Schomaker ◽  
Gary Maartens ◽  
Richard A. Murphy
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Second Line ◽  
Second Line Antiretroviral Therapy

scholarly journals Sustained Virological Response on Second-Line Antiretroviral Therapy following Virological Failure in HIV-Infected Patients in Rural South Africa

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58526 ◽  
Author(s):  
Annelot F. Schoffelen ◽  
Annemarie M. J. Wensing ◽  
Hugo A. Tempelman ◽  
Sibyl P. M. Geelen ◽  
Andy I. M. Hoepelman ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Sustained Virological Response ◽  
Virological Failure ◽  
Virological Response ◽  
Second Line ◽  
Rural South ◽  
Rural South Africa ◽  
Second Line Antiretroviral Therapy
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