scholarly journals Long-Term Virologic Response and Genotypic Resistance Mutations in HIV-1 Infected Kenyan Children on Combination Antiretroviral Therapy

2013 ◽  
Vol 62 (3) ◽  
pp. 267-274 ◽  
Author(s):  
Dalton C. Wamalwa ◽  
Dara A. Lehman ◽  
Sarah Benki-Nugent ◽  
Melanie A. Gasper ◽  
Richard Gichohi ◽  
...  
AIDS ◽  
2015 ◽  
Vol 29 (16) ◽  
pp. 2139-2148 ◽  
Author(s):  
Marloes A.M. Janssen ◽  
Olga Meulenbroek ◽  
Stefan C.A. Steens ◽  
Bozena Góraj ◽  
Marjolein Bosch ◽  
...  

2018 ◽  
Vol 14 (3) ◽  
pp. 435-444 ◽  
Author(s):  
Mohamed G. Atta ◽  
Sophie De Seigneux ◽  
Gregory M. Lucas

The success of combination antiretroviral therapy in the treatment of HIV-1–positive individuals has shifted clinical attention toward combination antiretroviral drug regimens that optimize tolerability, long-term safety, and durable efficacy. Wherever patients have access to treatment, morbidity and mortality are increasingly driven by non–HIV-associated comorbidities, which may be observed earlier than in age-matched controls and despite the best available combination antiretroviral therapy. Similarly, HIV-1–positive individuals are now diagnosed and treated earlier with anticipated lifelong therapy. The contribution of specific antiretroviral agents to long-term morbidity and mortality is dependent on the pharmacologic characteristics of these agents, and it is increasingly important in this context.


AIDS ◽  
2010 ◽  
Vol 24 (12) ◽  
pp. 1867-1876 ◽  
Author(s):  
Judith J Lok ◽  
Ronald J Bosch ◽  
Constance A Benson ◽  
Ann C Collier ◽  
Gregory K Robbins ◽  
...  

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