Clinical Importance of Incidentally Detected Hyperenhancing Liver Observations on Portal Venous Phase Computed Tomography in Patients Without Known Malignancy or Liver Disease

55-year-old woman with chronic liver disease Axial fat-suppressed FSE T2-weighted images (Figure 2.23.1) demonstrate a cirrhotic liver with diffuse, innumerable, small low-signal-intensity nodules. Axial arterial, portal venous, and hepatobiliary phase postgadolinium (Eovist) 3D SPGR images (Figure 2.23.2) demonstrate heterogeneous enhancement of the background parenchyma, particularly in the right hepatic lobe. The multiple nodules are initially hypointense on arterial and portal venous phase images but become hyperintense relative to adjacent liver on the hepatobiliary phase image....

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Value of CT Imaging in the Differentiation of Gastric Leiomyoma From Gastric Stromal Tumor

Canadian Association of Radiologists Journal ◽

10.1177/0846537119885671 ◽

2020 ◽

pp. 084653711988567

Author(s):

Jian Wang ◽

Xiaoxuan Zhou ◽

Fangyi Xu ◽

Weiqun Ao ◽

Hongjie Hu

Keyword(s):

Computed Tomography ◽

Multivariate Logistic Regression Analysis ◽

Fisher Exact Test ◽

Exact Test ◽

Portal Venous Phase ◽

Ct Value ◽

Unenhanced Ct ◽

Gastric Stromal Tumor ◽

Venous Phase ◽

Gastric Leiomyoma

Purpose: To discuss significant computed tomography (CT) findings that differentiate gastric leiomyomas (GLs) from small gastric stromal tumors (GSTs). Methods: One hundred sixty cases with pathologically proven GLs (n = 50) and GSTs (n = 110) with comprehensive CT images were enrolled in this retrospective study. Computed tomography findings (ie, size, location, contour, growth pattern, enhancement degree, necrosis, ulceration, calcification, and lymph nodes) were analyzed through the χ2 or Fisher exact test, independent T test, and multivariate (logistic regression) analysis. Sensitivity and specificity were also calculated. Results: Features of cardia location, endophytic growth, homogeneous gradual enhancement, absent of necrosis, long diameter less than 24 mm, short diameter less than 20 mm, unenhanced CT value larger than 35.2 Hounsfield units (HU), portal venous phase CT value larger than 67.4 HU, and enhancement degree of arterial and venous phase less than 16.2 HU and 32.4 HU were found to be statistically significant between GLs and small GSTs ( P < .05). On multivariate analysis, cardia location, endophytic growth, and homogeneous gradual enhancement were independent predictive factors for GLs and small GSTs. Conclusion: These 10 CT criteria are very helpful to differentiate GLs from small GSTs. Especially cardia location, endophytic growth, and homogeneous gradual enhancement are of high value in differential diagnosis.

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Gadoxetic acid-enhanced MRI for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: can hypointensity on the late portal venous phase be used as an alternative to washout?

Abdominal Radiology ◽

10.1007/s00261-020-02553-z ◽

2020 ◽

Vol 45 (9) ◽

pp. 2705-2716

Author(s):

Kyoung A. Baek ◽

Seung Soo Kim ◽

Hyeong Cheol Shin ◽

Jeong Ah Hwang ◽

Seo-Youn Choi ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Disease ◽

Chronic Liver Disease ◽

Chronic Liver ◽

Gadoxetic Acid ◽

Portal Venous Phase ◽

Enhanced Mri ◽

Venous Phase

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Axial computed tomography of a male pelvis in the portal venous phase post-contrast

BMJ ◽

10.1136/bmj.e6433 ◽

2012 ◽

Vol 345 (oct01 2) ◽

pp. e6433-e6433

Author(s):

R. H. Kassamali ◽

S. J. Karia

Keyword(s):

Computed Tomography ◽

Post Contrast ◽

Portal Venous Phase ◽

Venous Phase

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Aortic and Hepatic Contrast Enhancement During Hepatic-Arterial and Portal Venous Phase Computed Tomography Scanning

Journal of Computer Assisted Tomography ◽

10.1097/rct.0000000000000513 ◽

2017 ◽

Vol 41 (2) ◽

pp. 309-314 ◽

Cited By ~ 5

Author(s):

Takanori Masuda ◽

Takeshi Nakaura ◽

Yoshinori Funama ◽

Toru Higaki ◽

Masao Kiguchi ◽

...

Keyword(s):

Computed Tomography ◽

Contrast Enhancement ◽

Portal Venous Phase ◽

Computed Tomography Scanning ◽

Venous Phase ◽

Tomography Scanning

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Spectrum of Fontan-associated liver disease assessed by MRI and US in young adolescents

Abdominal Radiology ◽

10.1007/s00261-021-02994-0 ◽

2021 ◽

Author(s):

Karl Julius Thrane ◽

Lil Sofie Ording Müller ◽

Kathrine Rydén Suther ◽

Kristian Stien Thomassen ◽

Henrik Holmström ◽

...

Keyword(s):

Liver Disease ◽

Fontan Circulation ◽

Imaging Findings ◽

Portal Venous Phase ◽

National Cohort ◽

Hepatic Imaging ◽

Venous Phase ◽

Magnetic Resonance Imaging Mri ◽

Serological Data ◽

Imaging Signs

Abstract Purpose Patients with Fontan circulation are at risk of developing hepatic fibrosis/cirrhosis. The mechanisms and disease development are unclear and early secondary liver cancer is a concern. This study will describe hepatic imaging findings in a national cohort of adolescents with Fontan circulation. Methods The patients prospectively underwent abdominal contrast enhanced magnetic resonance imaging (MRI) including diffusion-weighted imaging. Images were assessed for criteria of fibrosis/cirrhosis including characterization of hepatic nodules. These nodules were in addition, assessed by ultrasonography (US). Nodules ≥ 1 cm were investigated and monitored to evaluate malignant transformation. Clinical and hepatic serological data were recorded. Results Forty-six patients, median age of 16.5 years (15.4–17.9 years) were enrolled. All patients underwent US examination and MRI was performed in 35/46 patients. On MRI, 60% had hepatomegaly and 37% had signs of fibrosis/cirrhosis. Seven patients had together 13 nodules ≥ 1 cm in diameter. Only 4/13 (17%) where seen on US. Nodules had variable MRI signal characteristics including hepatobiliary contrast enhancement and two nodules revealed portal venous phase ‘wash-out’ on the first examination. No further imaging signs of malignancy were revealed during the follow-up period of median 24.4 (7–42) months. Conclusion The majority of adolescents with Fontan circulation had imaging findings of fibrosis/cirrhosis of varying severity. US had low detection rate of hepatic nodules compared to MRI. The imaging work-up before transition to adult cardiology care did not reveal findings suggestive of malignancy. However, the high prevalence of Fontan-associated liver disease calls for surveillance strategies even in childhood.

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