Cerebral Perfusion Imaging for Intravenous Thrombolysis Treatment

2021 ◽  
Vol 30 (4) ◽  
pp. 205-209
Author(s):  
Diana E. Slawski, MD ◽  
Gregory W. Albers, MD
Keyword(s):  
Perfusion Imaging ◽  
Cerebral Perfusion ◽  
Intravenous Thrombolysis

Intracerebral hemorrhage after carotid endarterectomy associated with asymptomatic perioperative cerebral ischemia detected by cerebral perfusion imaging: Case report

2004 ◽  
Vol 62 (4) ◽  
pp. 319-322 ◽  
Author(s):  
Kuniaki Ogasawara ◽  
Takashi Inoue ◽  
Masakazu Kobayashi ◽  
Hidehiko Endo ◽  
Takeshi Fukuda ◽  
...  
Keyword(s):  
Case Report ◽  
Cerebral Ischemia ◽  
Intracerebral Hemorrhage ◽  
Carotid Endarterectomy ◽  
Perfusion Imaging ◽  
Cerebral Perfusion

Abstract 1122‐000084: Does Intravenous Thrombolysis Promote Delayed Reperfusion After Incomplete Mechanical Thrombectomy?

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Adnan Mujanovic ◽  
Christoph Kammer ◽  
Christoph C Kurmann ◽  
Lorenz Grunder ◽  
Morin Beyeler ◽  
...  
Keyword(s):  
Perfusion Imaging ◽  
Mechanical Thrombectomy ◽  
Intravenous Thrombolysis ◽  
Functional Independence ◽  
Considerable Proportion ◽  
Time Interval ◽  
Start Time ◽  
Vessel Occlusion ◽  
Stroke Registry

Introduction : The value of intravenous thrombolysis (IVT) in patients eligible for mechanical thrombectomy (MT) remains unclear. We hypothesized that pre‐treatment with and/or ongoing IVT may facilitate reperfusion of distal vessel occlusion after incomplete MT. We evaluated this potential association using follow‐up perfusion imaging. Methods : Retrospective observational analysis of our institution`s stroke registry included patients with incomplete reperfusion after MT, admitted between February 1, 2015 and December 8, 2020. Delayed reperfusion (DR) was defined as the absence of a persistent perfusion deficit on contrast‐enhanced perfusion imaging ⁓24h±12h after the intervention. The association between baseline parameters and the occurrence of DR was evaluated using a logistic regression analyses. To account for possible time‐dependent associations of IVT with DR, additional stratification sets were made based on different time windows between IVT start time and final angiography runs. Results : Among the 378 included patients (median age 73.5, 50.8% female), DR occurred in 226 (59.8%). Atrial fibrillation (aOR 2.53 [95% CI 1.34 ‐ 4.90]), eTICI score (aOR 3.79 [95% CI 2.71 ‐ 5.48] per TICI grade increase), and intervention‐to‐follow‐up time (aOR 1.08 [95% CI 1.04 ‐ 1.13] per hour delay) were associated with DR. Dichotomized IVT strata showed no association with DR (aOR 0.75 [95% CI 0.42 ‐ 1.33]), whereas shorter intervals between IVT start and end of the procedure showed a borderline significant association with DR (OR 2.24 [95% CI 0.98 ‐ 5.43, and OR 2.07 [95% 1.06 – 4.31], for 80 and 100 minutes respectively). Patients with DR had higher rates of functional independence (modified Rankin scale 0–2 at 90 days, DR: 63.3% vs PPD: 38.8%; p<0.01) and longer survival time (at 3 years, DR: 69.2% vs PPD: 45.8%; p = 0.001). Conclusions : There is weak evidence that IVT may favor DR after incomplete MT if the time interval between IVT administration and end of the procedure is short. In general, perfusion follow‐up imaging may constitute a suitable surrogate parameter for evaluating medical rescue strategies after incomplete MT, because a considerable proportion of patients do not experience DR, and there seems to be a close correlation with clinical outcomes.

scholarly journals Minimizing macrovessel signal in cerebral perfusion imaging using independent component analysis

2007 ◽  
Vol 57 (2) ◽  
pp. 278-288 ◽  
Author(s):  
G. Reishofer ◽  
F. Fazekas ◽  
S. Keeling ◽  
C. Enzinger ◽  
F. Payer ◽  
...  
Keyword(s):  
Independent Component Analysis ◽  
Perfusion Imaging ◽  
Cerebral Perfusion ◽  
Component Analysis ◽  
Independent Component

Cerebral perfusion imaging

2015 ◽  
pp. 59-68
Author(s):  
Linda Knutsson ◽  
Birgitte Fuglsang Kjølby
Keyword(s):  
Perfusion Imaging ◽  
Cerebral Perfusion

scholarly journals Diagnostic accuracy of flat-panel computed tomography in assessing cerebral perfusion in comparison with perfusion computed tomography and perfusion magnetic resonance: a systematic review

2019 ◽  
Vol 61 (12) ◽  
pp. 1457-1468 ◽  
Author(s):  
Ernst L. Stille ◽  
Ilaria Viozzi ◽  
Mark ter Laan ◽  
Frederick J.A. Meijer ◽  
Jurgen J. Futterer ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systematic Review ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Cerebrovascular Disease ◽  
Blood Volume ◽  
Perfusion Imaging ◽  
Cerebral Perfusion ◽  
Flat Panel ◽  
Perfusion Computed Tomography

Abstract Purpose Flat-panel computed tomography (FP-CT) is increasingly available in angiographic rooms and hybrid OR’s. Considering its easy access, cerebral imaging using FP-CT is an appealing modality for intra-procedural applications. The purpose of this systematic review is to assess the diagnostic accuracy of FP-CT compared with perfusion computed tomography (CTP) and perfusion magnetic resonance (MRP) in cerebral perfusion imaging. Methods We performed a systematic literature search in the Cochrane Library, MEDLINE, Embase, and Web of Science up to June 2019 for studies directly comparing FP-CT with either CTP or MRP in vivo. Methodological quality was assessed using the QUADAS-2 tool. Data on diagnostic accuracy was extracted and pooled if possible. Results We found 11 studies comparing FP-CT with CTP and 5 studies comparing FP-CT with MRP. Most articles were pilot or feasibility studies, focusing on scanning and contrast protocols. All patients studied showed signs of cerebrovascular disease. Half of the studies were animal trials. Quality assessment showed unclear to high risks of bias and low concerns regarding applicability. Five studies reported on diagnostic accuracy; FP-CT shows good sensitivity (range 0.84–1.00) and moderate specificity (range 0.63–0.88) in detecting cerebral blood volume (CBV) lesions. Conclusions Even though FP-CT provides similar CBV values and reconstructed blood volume maps as CTP in cerebrovascular disease, additional studies are required in order to reliably compare its diagnostic accuracy with cerebral perfusion imaging.

Validation of the Depletion Kinetic in Semiquantitative Ultrasonographic Cerebral Perfusion Imaging Using 2 Different Techniques of Data Acquisition

2004 ◽  
Vol 23 (8) ◽  
pp. 1035-1040 ◽  
Author(s):  
Jens Eyding ◽  
Wilko Wilkening ◽  
Christos Krogias ◽  
Thilo Hölscher ◽  
Horst Przuntek ◽  
...  
Keyword(s):  
Data Acquisition ◽  
Perfusion Imaging ◽  
Cerebral Perfusion
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