In July 2021, Typhoon In-Fa attacked eastern China and broke many records for extreme precipitation over the last century. Such an unrivaled impact results from In-Fa’s slow moving speed and long residence time due to atmospheric circulations. With the supports of 66 networked surface disdrometers over eastern China and collaborative observations from the advanced GPM satellite, we are able to reveal the unique precipitation microphysical properties of the record-breaking Typhoon In-Fa (2021). After separating the typhoon precipitation into convective and stratiform types and comparing the drop size distribution (DSD) properties of Typhoon In-Fa with other typhoons from different climate regimes, it is found that typhoon precipitation shows significant internal differences as well as regional differences in terms of DSD-related parameters, such as mass-weighted mean diameter (Dm), normalized intercept parameter (Nw), radar reflectivity (Z), rain rate (R), and intercept, shape, and slope parameters (N0, µ, Λ). Comparing different rain types inside Typhoon In-Fa, convective rain (Nw ranging from 3.80 to 3.96 mm−1 m−3) shows higher raindrop concentration than stratiform rain (Nw ranging from 3.40 to 3.50 mm−1 m−3) due to more graupels melting into liquid water while falling. Large raindrops occupy most of the region below the melting layer in convective rain due to a dominant coalescence process of small raindrops (featured by larger ZKu, Dm, and smaller N0, µ, Λ), while small raindrops account for a considerable proportion in stratiform rain, reflecting a significant collisional breakup process of large raindrops (featured by smaller ZKu, Dm, and larger N0, µ, Λ). Compared with other typhoons in Hainan and Taiwan, the convective precipitation of Typhoon In-Fa shows a larger (smaller) raindrop concentration than that of Taiwan (Hainan), while smaller raindrop diameter than both Hainan and Taiwan. Moreover, the typhoon convective precipitation measured in In-Fa is more maritime-like than precipitation in Taiwan. Based on a great number of surface disdrometer observational data, the GPM precipitation products were further validated for both rain types, and a series of native quantitative precipitation estimation relations, such as Z–R and R–Dm relations were derived to improve the typhoon rainfall retrieval for both ground-based radar and spaceborne radar.