Transplantation With Autologous Mesenchymal Stem Cells After Acute Myocardial Infarction Evaluated by Magnetic Resonance Imaging

2012 ◽  
Vol 27 (2) ◽  
pp. 125-135 ◽  
Author(s):  
Minjie Lu ◽  
Shihua Zhao ◽  
Qiong Liu ◽  
Shiliang Jiang ◽  
Peng Song ◽  
...  
2021 ◽  
Vol 14 (2) ◽  
pp. 136-139
Author(s):  
Inna Evgenievna Kotkas ◽  
Shamil Magomedovich Asadulaev ◽  
Natella Iosifovna Enukashvili

To date, there are quite a large number of reports of the use of stem cells in the treatment of various diseases in humans. However, the authors do not provide credible evidence that the introduced stem cells come directly into the target organ. Without a clear understanding of the location of the introduced stem cells, it is difficult to reliably assess the effect of their use. The article gives its own observation about the possibility of imaging in the human body autologous mesenchymal stem cells introduced through the portal vein of the liver to a patient suffering from cirrhosis. Iron oxide nanoparticles were used as labels. A rather simple question was previously solved: how to create a label of such size that the viability of the stem cell was preserved and it could be visualized in the human body when performing magnetic resonance imaging of abdominal organs. Following in vitro studies, the most appropriate stem cell marking embodiment was chosen to provide both adequate imaging and cell viability. After administration of marked table cells, magnetic resonance imaging of abdominal organs was performed to the patient. The introduced stem cells were visualised only in hepatic tissue. According to clinical and biochemical blood tests - no deviations were detected. There were no complications against the background of this procedure. The patient was discharged for outpatient treatment in satisfactory condition.


Circulation ◽  
2003 ◽  
Vol 107 (18) ◽  
pp. 2290-2293 ◽  
Author(s):  
Dara L. Kraitchman ◽  
Alan W. Heldman ◽  
Ergin Atalar ◽  
Luciano C. Amado ◽  
Bradley J. Martin ◽  
...  

2008 ◽  
Vol 35 (6Part21) ◽  
pp. 2898-2898
Author(s):  
Y Yang ◽  
Y Yang ◽  
B Klein ◽  
N Yanasak ◽  
X Shi ◽  
...  

1997 ◽  
Vol 80 (6) ◽  
pp. 690-695 ◽  
Author(s):  
Christopher M Kramer ◽  
Walter J Rogers ◽  
Gennady Geskin ◽  
Thomas P Power ◽  
Therese M Theobald ◽  
...  

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