Determination of a Perfusion Threshold in Experimental Perforator Flap Surgery Using Indocyanine Green Angiography

2014 ◽  
Vol 73 (5) ◽  
pp. 602-606 ◽  
Author(s):  
John Monahan ◽  
Brian H. Hwang ◽  
James M. Kennedy ◽  
Wen Chen ◽  
Gerard K. Nguyen ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Indocyanine Green Angiography ◽  
Perforator Flap ◽  
Flap Surgery

The Impact of Indocyanine Green Angiography on Fat Necrosis in Deep Inferior Epigastric Perforator Flap Breast Reconstruction

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Aran Yoo ◽  
Patrick A. Palines ◽  
James L. Mayo ◽  
Matthew J. Bartow ◽  
Denise M. Danos ◽  
...  
Keyword(s):  
Breast Reconstruction ◽  
Indocyanine Green ◽  
Indocyanine Green Angiography ◽  
Perforator Flap ◽  
Fat Necrosis ◽  
Deep Inferior Epigastric Perforator ◽  
The Impact

Clearance and Non-Invasive Determination of the Hepatic Extraction of Indocyanine Green in Baboons and Man

1983 ◽  
Vol 64 (2) ◽  
pp. 207-212 ◽  
Author(s):  
S. L. Grainger ◽  
P. W. N. Keeling ◽  
I. M. H. Brown ◽  
J. H. Marigold ◽  
R. P. H. Thompson
Keyword(s):  
Indocyanine Green ◽  
Accurate Determination ◽  
Liver Blood Flow ◽  
Compartment Model ◽  
Hepatic Extraction ◽  
Non Invasive ◽  
Two Compartment Model ◽  
Hepatic Extraction Ratio ◽  
Plasma Disappearance Curve

1. The disposition of an intravenous bolus of indocyanine green (ICG) has been studied in healthy man and baboons using a novel analysis of a two compartment pharmacokinetic model. 2. This analysis enabled the hepatic extraction ratio (ER) of dye to be determined solely from the plasma disappearance curve, and the ER determined did not differ from that measured by hepatic vein catheterization. 3. When compared with clearance measured at steady state, the two compartment model gave a significantly more accurate determination of plasma clearance than did the conventional one compartment model. 4. It is concluded that, in health, liver blood flow may be calculated accurately and noninvasively after a single intravenous injection of ICG.

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