scholarly journals Lack of association between triggering receptor expressed on myeloid cells 2 polymorphism rs75932628 and late-onset Alzheimer’s disease in a Chinese Han population

2018 ◽  
Vol 28 (1) ◽  
pp. 16-18 ◽  
Author(s):  
Ping Wang ◽  
Qihao Guo ◽  
Yan Zhou ◽  
Keliang Chen ◽  
Yan Xu ◽  
...  
PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e63621 ◽  
Author(s):  
Wei Xu ◽  
Jun Xu ◽  
Ying Wang ◽  
Huidong Tang ◽  
Yulei Deng ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 627-630 ◽  
Author(s):  
Jian-Fang Ma ◽  
Li-hua Liu ◽  
Yu Zhang ◽  
Ying Wang ◽  
Yu-Lei Deng ◽  
...  

Objective: We conducted a case–control study to investigate whether clusterin polymorphism (rs11136000) was associated with late-onset Alzheimer’s disease in Chinese Han population. Methods: Polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) assay was performed on genotype rs11136000 and APOEε4 in 127 patients with late-onset Alzheimer’s disease and 143 control individuals. Previous published data from other Chinese samples was also included for further meta-analysis. Results: APOEε4 was demonstrated to increase the risk of Alzheimer’s disease in Chinese population (odds ratio = 2.35, 95% confidence interval: 1.40-3.96). There is no significant association between clusterin rs11136000 with late-onset sporadic AD in our small cohort. However, meta-analysis revealed significant allele and genotype differences between Alzheimer’s disease and controls following a recessive model. Conclusion: Clusterin (rs11136000) was associated with Alzheimer’s disease in Chinese Han population.


Oncotarget ◽  
2017 ◽  
Vol 8 (29) ◽  
pp. 48313-48320 ◽  
Author(s):  
Hui Zhang ◽  
Wei Zheng ◽  
Linlin Hua ◽  
Yutong Wang ◽  
Jinfeng Li ◽  
...  

2014 ◽  
Vol 36 (10) ◽  
pp. 894-896 ◽  
Author(s):  
Jianfang Ma ◽  
Yi Zhou ◽  
Jun Xu ◽  
Xiaohong Liu ◽  
Ying Wang ◽  
...  

2015 ◽  
Vol 593 ◽  
pp. 56-60 ◽  
Author(s):  
Huacheng Yan ◽  
Yanying Kong ◽  
Baoxia He ◽  
Mukun Huang ◽  
Jian Li ◽  
...  

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