scholarly journals Assembly of single-shelled cores and double-shelled virus-like particles after baculovirus expression of major structural proteins P3, P7 and P8 of Rice dwarf virus

2003 ◽  
Vol 84 (4) ◽  
pp. 981-984 ◽  
Author(s):  
Kyoji Hagiwara ◽  
Takahiko Higashi ◽  
Kazunori Namba ◽  
Tamaki Uehara-Ichiki ◽  
Toshihiro Omura
Keyword(s):  
Dwarf Virus ◽  
Structural Proteins ◽  
Rice Dwarf Virus ◽  
Virus Like Particles ◽  
Baculovirus Expression

scholarly journals Assembly of Double-Shelled, Virus-Like Particles in Transgenic Rice Plants Expressing Two Major Structural Proteins of Rice Dwarf Virus

2000 ◽  
Vol 74 (20) ◽  
pp. 9808-9810 ◽  
Author(s):  
Honghong Zheng ◽  
Li Yu ◽  
Chunhong Wei ◽  
Dongwei Hu ◽  
Yunping Shen ◽  
...  
Keyword(s):  
Transgenic Rice ◽  
Structural Integrity ◽  
Core Protein ◽  
Dwarf Virus ◽  
Structural Proteins ◽  
Rice Dwarf Virus ◽  
Virus Like Particles ◽  
Rice Plants ◽  
Transgenic Rice Plants ◽  
Core Proteins

ABSTRACT Rice dwarf virus (RDV) is a double-shelled particle that contains a major capsid protein (P8), a major core protein (P3), several minor core proteins, and viral genomic double-stranded RNA. Coexpression of P8 and P3 in transgenic rice plants resulted in formation of double-shelled, virus-like particles (VLPs) similar to the authentic RDV particles. The VLPs were not detected in transgenic rice plant cells expressing P8 alone. This in vivo result suggests that P8 interacted with P3 and that these two proteins provide the structural integrity required for the formation of VLPs in rice cells independently of other structural proteins, nonstructural proteins, or viral genomic double-stranded RNAs.

Double-stranded ribonucleic acid from rice dwarf virus

Virology ◽  
1966 ◽  
Vol 28 (4) ◽  
pp. 571-579 ◽  
Author(s):  
Kin-Ichiro Miura ◽  
Ikuo Kimura ◽  
Naoji Suzuki
Keyword(s):  
Ribonucleic Acid ◽  
Dwarf Virus ◽  
Rice Dwarf Virus

scholarly journals Nucleotide Sequence of Rice Dwarf Virus Genome Segment 9

1989 ◽  
Vol 70 (5) ◽  
pp. 1297-1300 ◽  
Author(s):  
I. Uyeda ◽  
H. Kudo ◽  
T. Takahashi ◽  
T. Sano ◽  
K. Ohshima ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Virus Genome ◽  
Genome Segment ◽  
Dwarf Virus ◽  
Rice Dwarf Virus

scholarly journals Aggregation Ability of Virus-Specific Antibodies is Correlated with their Capacity to Neutralize Rice dwarf virus

2012 ◽  
Vol 46 (1) ◽  
pp. 65-71
Author(s):  
Hongyan CHEN ◽  
Taiyun WEI ◽  
Ai SAOTOME ◽  
Kengo SAKAGUCHI ◽  
Yasuo SHIKAMOTO ◽  
...  
Keyword(s):  
Dwarf Virus ◽  
Rice Dwarf Virus ◽  
Specific Antibodies

Nucleotide Sequence of Rice Dwarf Phytoreovirus Genome Segment 2: Completion of Sequence Analyses of Rice Dwarf Virus

Intervirology ◽  
1994 ◽  
Vol 37 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Ichiro Uyeda ◽  
Narushi Suda ◽  
Naoki Yamada ◽  
Hiroshi Kudo ◽  
Kazunori Murao ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Genome Segment ◽  
Dwarf Virus ◽  
Rice Dwarf Virus ◽  
Sequence Analyses

scholarly journals Recent Progress on the Versatility of Virus-Like Particles

Vaccines ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 139 ◽  
Author(s):  
Ciying Qian ◽  
Xinlin Liu ◽  
Qin Xu ◽  
Zhiping Wang ◽  
Jie Chen ◽  
...  
Keyword(s):  
Immune Responses ◽  
Small Molecules ◽  
Genetic Material ◽  
Structural Proteins ◽  
Cell Penetration ◽  
Virus Like Particles ◽  
Humoral Immune ◽  
Specific Targeting ◽  
Humoral Immune Responses ◽  
Antigenic Epitopes

Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural proteins of a virus in the absence of genetic material. Having similar morphology to natural viruses but lacking any pathogenicity or infectivity, VLPs have gradually become a safe substitute for inactivated or attenuated vaccines. VLPs can achieve tissue-specific targeting and complete and effective cell penetration. With highly ordered epitope repeats, VLPs have excellent immunogenicity and can induce strong cellular and humoral immune responses. In addition, as a type of nanocarrier, VLPs can be used to display antigenic epitopes or deliver small molecules. VLPs have thus become powerful tools for vaccinology and biomedical research. This review highlights the versatility of VLPs in antigen presentation, drug delivery, and vaccine technology.

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