Potential cross-protection against SARS-CoV-2 from previous exposure to bovine coronavirus
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Humans have long shared infectious agents with cattle, and the common cold OC-43 CoV is a not-so-distant example of cross-species viral spillover. Human exposure to BCoV is certainly common, as the virus is endemic in cattle-raising regions. This article shows an in silico investigation of shared viral epitopes between BCoV and SARS-CoV-2. HLA recognition and lymphocyte reactivity were assessed using freely-available resources. Several epitopes were shared between BCoV and SARS-CoV-2, both for B and T lymphocytes. These data demonstrate that possible cross-protection is being induced by human exposure to cattle.
A Clinical Trial of Hypertonic Saline Nasal Spray in Subjects With the Common Cold or Rhinosinusitis
1998 ◽
Vol 7
(1)
◽
pp. 39-43
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2020 ◽
Vol 10
(1)
◽
pp. 1-8
Keyword(s):
2015 ◽
Vol 30
(suppl_3)
◽
pp. iii511-iii511
Keyword(s):
Keyword(s):