scholarly journals Empirically Based Guidelines for Selecting Vagus Nerve Stimulation Parameters in Epilepsy and Heart Failure

2018 ◽  
Vol 9 (7) ◽  
pp. a034264 ◽  
Author(s):  
Eric D. Musselman ◽  
Nicole A. Pelot ◽  
Warren M. Grill
Keyword(s):  
Heart Failure ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Stimulation Parameters

scholarly journals Effect of defibrillation on the performance of an implantable vagus nerve stimulation system

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Imad Libbus ◽  
Scott R. Stubbs ◽  
Scott T. Mazar ◽  
Scott Mindrebo ◽  
Bruce H. KenKnight ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Function ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Pulse Generator ◽  
High Energy ◽  
Implantable Pulse Generator ◽  
Defibrillation Pulse ◽  
Stimulation System

Abstract Background Vagus Nerve Stimulation (VNS) delivers Autonomic Regulation Therapy (ART) for heart failure (HF), and has been associated with improvement in cardiac function and heart failure symptoms. VNS is delivered using an implantable pulse generator (IPG) and lead with electrodes placed around the cervical vagus nerve. Because HF patients may receive concomitant cardiac defibrillation therapy, testing was conducted to determine the effect of defibrillation (DF) on the VNS system. Methods DF testing was conducted on three ART IPGs (LivaNova USA, Inc.) according to international standard ISO14708-1, which evaluated whether DF had any permanent effects on the system. Each IPG was connected to a defibrillation pulse generator and subjected to a series of high-energy pulses. Results The specified series of pulses were successfully delivered to each of the three devices. All three IPGs passed factory electrical tests, and interrogation confirmed that software and data were unchanged from the pre-programmed values. No shifts in parameters or failures were observed. Conclusions Implantable VNS systems were tested for immunity to defibrillation, and were found to be unaffected by a series of high-energy defibrillation pulses. These results suggest that this VNS system can be used safely and continue to function after patients have been defibrillated.

Right Vagus Nerve Stimulation With a Novel Self-Sizing Cuff Electrode Improves Left Ventricular Function in Dogs With Heart Failure

2015 ◽  
Vol 21 (8) ◽  
pp. S93 ◽  
Author(s):  
Hani N. Sabbah ◽  
Mengjun Wang ◽  
Kefei Zhang ◽  
Ramesh C. Gupta ◽  
Maxime Lemonnier ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Function ◽  
Vagus Nerve ◽  
Ventricular Function ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Left Ventricular ◽  
Cuff Electrode

Acute effect of Vagus nerve stimulation parameters on cardiac chronotropic, inotropic, and dromotropic responses

2017 ◽  
Author(s):  
Alfredo I. Hernández ◽  
David Ojeda ◽  
Virginie Le Rolle ◽  
Hector Romero Ugalde ◽  
Clément Gallet ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Acute Effect ◽  
Stimulation Parameters

scholarly journals RIGHT VAGUS NERVE STIMULATION IMPROVES LEFT VENTRICULAR FUNCTION IN DOGS WITH HEART FAILURE

2010 ◽  
Vol 55 (10) ◽  
pp. A16.E151 ◽  
Author(s):  
Hani N. Sabbah ◽  
Mengjun Wang ◽  
Alice Jiang ◽  
Stephen B. Ruble ◽  
Jason J. Hamann
Keyword(s):  
Heart Failure ◽  
Left Ventricular Function ◽  
Vagus Nerve ◽  
Ventricular Function ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Left Ventricular
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