This chapter attempts to calculate the radiated energy of a source in the linear approximation of general relativity to infinity in the lowest order. For this, the chapter first expands the Einstein equations to quadratic order in metric perturbations. It reveals that the radiated energy is then given by the (second) quadrupole formula, which is the gravitational analog of the dipole formula in Maxwell theory. This formula is a priori valid only if the motion of the source is due to forces other than gravity. Finally, this chapter shows that, to prove this formula for the case of self-gravitating systems, the Einstein equations to quadratic order must be solved, and the radiative field in the post-linear approximation of general relativity obtained.