Electric-field-sustained spiral waves in subexcitable media

2012 ◽  
Vol 86 (1) ◽  
Author(s):  
Mei-chun Cai ◽  
Jun-ting Pan ◽  
Hong Zhang
Keyword(s):  
Author(s):  
Shreyas Punacha ◽  
Sebastian Berg ◽  
Anupama Sebastian ◽  
Valentin I. Krinski ◽  
Stefan Luther ◽  
...  

Rotating spiral waves of electrical activity in the heart can anchor to unexcitable tissue (an obstacle) and become stable pinned waves. A pinned rotating wave can be unpinned either by a local electrical stimulus applied close to the spiral core, or by an electric field pulse that excites the core of a pinned wave independently of its localization. The wave will be unpinned only when the pulse is delivered inside a narrow time interval called the unpinning window (UW) of the spiral. In experiments with cardiac monolayers, we found that other obstacles situated near the pinning centre of the spiral can facilitate unpinning. In numerical simulations, we found increasing or decreasing of the UW depending on the location, orientation and distance between the pinning centre and an obstacle. Our study indicates that multiple obstacles could contribute to unpinning in experiments with intact hearts.


2014 ◽  
Vol 140 (18) ◽  
pp. 184901 ◽  
Author(s):  
Bing-Wei Li ◽  
Mei-Chun Cai ◽  
Hong Zhang ◽  
Alexander V. Panfilov ◽  
Hans Dierckx

2021 ◽  
Author(s):  
Karthikeyan Rajagopal ◽  
Irene Moroz ◽  
Balamurali Ramakrishnan ◽  
Anitha Karthikeyan ◽  
Prakash Duraisamy

Abstract A Morris-Lecar neuron model is considered with Electric and Magnetic field effects where the electric field is a time varying sinusoid and magnetic field is simulated using an exponential flux memristor. We have shown that the exposure to electric and magnetic fields have significant effects on the neurons and have exhibited complex oscillations. The neurons exhibit a frequency-locked state for the periodic electric field and different ratios of frequency locked states with respect to the electric field frequency is also presented. To show the impact of the electric and magnetic fields on network of neurons, we have constructed different types of network and have shown the network wave propagation phenomenon. Interestingly the nodes exposed to both electric and magnetic fields exhibit more stable spiral waves compared to the nodes exhibited only to the magnetic fields. Also, when the number of layers are increased the range of electric field frequency for which the layers exhibit spiral waves also increase. Finally the noise effects on the field affected neuron network are discussed and multilayer networks supress spiral waves for a very low noise variance compared against the single layer network.


ChemPhysChem ◽  
2001 ◽  
Vol 2 (10) ◽  
pp. 613-616 ◽  
Author(s):  
Michael Seipel ◽  
Matthias Zierhut ◽  
Arno F. Münster

1992 ◽  
Vol 68 (2) ◽  
pp. 248-251 ◽  
Author(s):  
O. Steinbock ◽  
J. Schütze ◽  
S. C. Müller

1994 ◽  
Vol 04 (05) ◽  
pp. 1173-1182 ◽  
Author(s):  
P. COULLET ◽  
F. PLAZA

A mechanical analog of the chemical and biological excitable medium is proposed. In nematic liquid crystals, the Freedericksz transition induced by a rotating tilted electric field provides a simple example of such a mechanical excitable system. We study this transition, derive a Ginzburg-Landau model for it, and show that the excitable spiral wave can be produced from a retractable finger-like soliton in this context.


2006 ◽  
Vol 124 (1) ◽  
pp. 014505 ◽  
Author(s):  
Jiang-Xing Chen ◽  
Hong Zhang ◽  
You-Quan Li
Keyword(s):  

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