Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae
2018 ◽
Vol 74
(5)
◽
pp. 315-321
◽
Keyword(s):
The structure of the tandem lipid-binding PX and pleckstrin-homology (PH) domains of the Cdc42 GTPase-activating protein Bem3 from Saccharomyces cerevisiae (strain S288c) has been determined to a resolution of 2.2 Å (R work = 21.1%, R free = 23.4%). It shows that the domains adopt a relative orientation that enables them to simultaneously bind to a membrane and suggests possible cooperativity in membrane binding.
2002 ◽
Vol 277
(30)
◽
pp. 27412-27422
◽
Keyword(s):
2004 ◽
Vol 32
(5)
◽
pp. 707-711
◽
Keyword(s):