Using adaptive networks to model and control drug delivery

IEEE Expert ◽  
1996 ◽  
Vol 11 (2) ◽  
pp. 31-37 ◽  
Author(s):  
J.Y. Conway ◽  
M.M. Polycarpou
Author(s):  
Matin Sadat Saneei Mousavi ◽  
Amir Hossein Karami ◽  
Mehrshad Ghasemnejad ◽  
Mohammadreza Kolahdouz ◽  
Faranak Manteghi ◽  
...  

2014 ◽  
Vol 911 ◽  
pp. 336-341 ◽  
Author(s):  
Maria Mucha ◽  
Iwona Socha-Michalak ◽  
Jacek Balcerzak

In the paper the results of control drug release from different forms of carriers are presented. Dibutyrylchitin, chitosan, polylactid acid and polycaprolactone have been used as matrices for delivery of therapeutic substances (ibuprofen and salicylic acid). Two configurations of matrices for drug delivery have been found. Flat drug delivery systems (films) and spherical matrices (beads) were tested in the aim of control drug transport. To control the drug release, matrices have been modified. The release of active substances from films has been tested in buffer solution of pH 5.5. Spherical matrices have been tested in buffer solutions of pH 1.4 and pH 7.2. To experimental data First order and two stage models were fitted.


2020 ◽  
Vol 10 (4) ◽  
pp. 326-341
Author(s):  
Vikas Jhawat ◽  
Monika Gulia ◽  
Balaji Maddiboyina ◽  
Rohit Dutt ◽  
Sumeet Gupta

Hydrogels are a class of biomaterial that can “take in” large quantities of aqueous media and swells many times larger than its original size without dissolving in the media. SPHs are a new generation of hydrogels containing a 3D network of cross-linked polymers having pore size more than 100 μm as compared to 10 nm to 10 μm pores of conventional gels. These are more complex in nature than conventional hydrogels and prepared by using a suitable blend of monomers and different additives. SPHs have been extensively employed in sustained and control drug delivery systems along with many recent biomedical applications such as in tissue engineering, immunotherapy, arthritis and ophthalmic drug delivery. Scientists are constantly working on improving the features and properties of SPHs to enable them more suitable for therapeutic and biomedical applications. The present study briefly reviews the composition, evaluation and applications of SPHs in different areas. Applications are facilitated by the fact that SPHs are generally biocompatible in nature and resemble natural living tissue more than any other class of synthetic biomaterial.


2020 ◽  
Vol 17 (5) ◽  
pp. 1482-1490 ◽  
Author(s):  
Bridie Dutton ◽  
Arcadia Woods ◽  
Robyn Sadler ◽  
David Prime ◽  
David J. Barlow ◽  
...  

2017 ◽  
Vol 268 ◽  
pp. 72-77 ◽  
Author(s):  
Simon Vanstone ◽  
Sarah F. Cordery ◽  
James M. Stone ◽  
Sergey N. Gordeev ◽  
Richard H. Guy

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