A Nested Invocation Suppression Mechanism for Cctive Replicated SOAP Systems

Author(s):  
Chen-Liang Fang ◽  
Deron Liang ◽  
Fengyi Lin
2021 ◽  
Vol 224 ◽  
pp. 108637
Author(s):  
Zhen Bi ◽  
Lingxin Zhang ◽  
Xueming Shao

2001 ◽  
Vol 106 (A3) ◽  
pp. 3655-3663 ◽  
Author(s):  
Michael Mendillo ◽  
John Meriwether ◽  
Manfred Biondi

Author(s):  
Paolo E. Santangelo ◽  
Paolo Tartarini ◽  
Beatrice Pulvirenti ◽  
Paolo Valdiserri ◽  
Andre´ W. Marshall

Water-mist systems have become a promising technology in the fire-fighting field over the last twenty years. The present work is aimed at employing the available knowledge on water-mist sprays in an experimental and numerical analysis of the suppression mechanism. Therefore, a water-mist system has been operated within a typical fire case. Most notably, this latter is constituted by a heptane pool fire: experiments have been carried out inside a test chamber, where a set of thermocouples has conveniently been placed to evaluate the thermal transient at different locations of interest. Some free-combustion tests have been run as a benchmark to validate combustion models. Then, a typical water-mist nozzle has been inserted and activated to realize control, suppression and potential extinction of the generated fire. The recognized FDS (Fire Dynamics Simulator) and Fluent® codes have been challenged in reproducing the test case: thermal transient and suppression time have been considered as parameters for validation. Therefore, the water-mist spray has been modeled and the already mentioned results about its characterization have been implemented as initial or boundary conditions. Moreover, the fire scenario has been modeled as well. A good agreement between experimental and numerical results has been obtained, even under some approximations, with specific reference to combustion mechanisms.


1994 ◽  
Vol 09 (01) ◽  
pp. 41-50 ◽  
Author(s):  
KEN-ITI MATUMOTO ◽  
DAIJIRO SUEMATSU

We apply the empirical quark mass matrices to the lepton sector and study the solar neutrino problem and the atmospheric vμ deficit problem simultaneously. We show that their consistent explanation is possible on the basis of these matrices. The lepton sector mass matrices need the phase structure which is different from the ones of the quark sector. However, even if the phase structure of the mass matrices is identical in both sectors, an interesting suppression mechanism of sin 2 2θ12 which is related to the solar neutrino problem can be induced from the right-handed neutrino Majorana mass matrix. We discuss such a possibility through the concrete examples.


2019 ◽  
Vol 132 ◽  
pp. 185-198 ◽  
Author(s):  
Shenglun Zhang ◽  
Hua Xu ◽  
Lei Zhang ◽  
Yu Xing ◽  
Yanan Guo

2016 ◽  
Vol 2016 ◽  
pp. 1-9
Author(s):  
Pingyan Shi ◽  
Xiaohui Liu ◽  
Xiaofeng Tao ◽  
Jianchao Ji

A hybrid multiuser detection (MUD) using code mapping and a wrong code recognition based on relevance vector machine (RVM) for direct sequence ultra wide band (DS-UWB) system is developed to cope with the multiple access interference (MAI) and the computational efficiency. A new MAI suppression mechanism is studied in the following steps: firstly, code mapping, an optimal decision function, is constructed and the output candidate code of the matched filter is mapped to a feature space by the function. In the feature space, simulation results show that the error codes caused by MAI and the single user mapped codes can be classified by a threshold which is related to SNR of the receiver. Then, on the base of code mapping, use RVM to distinguish the wrong codes from the right ones and finally correct them. Compared with the traditional MUD approaches, the proposed method can considerably improve the bit error ratio (BER) performance due to its special MAI suppression mechanism. Simulation results also show that the proposed method can approximately achieve the BER performance of optimal multiuser detection (OMD) and the computational complexity approximately equals the matched filter. Moreover, the proposed method is less sensitive to the number of users.


mBio ◽  
2017 ◽  
Vol 8 (2) ◽  
Author(s):  
Jyoti K. Jha ◽  
Mi Li ◽  
Rodolfo Ghirlando ◽  
Lisa M. Miller Jenkins ◽  
Alexander Wlodawer ◽  
...  

ABSTRACTReplication ofVibrio choleraechromosome 2 (Chr2) depends on molecular chaperone DnaK to facilitate binding of the initiator (RctB) to the replication origin. The binding occurs at two kinds of site, 12-mers and 39-mers, which promote and inhibit replication, respectively. Here we show that DnaK employs different mechanisms to enhance the two kinds of binding. We found that mutations inrctBthat reduce DnaK binding also reduce 12-mer binding and initiation. The initiation defect is suppressed by second-site mutations that increase 12-mer binding only marginally. Instead, they reduce replication inhibitory mechanisms: RctB dimerization and 39-mer binding. One suppressing change was in a dimerization domain which is folded similarly to the initiator of an iteron plasmid—the presumed progenitor of Chr2. In plasmids, DnaK promotes initiation by reducing dimerization. A different mutation was in the 39-mer binding domain of RctB and inactivated it, indicating an alternative suppression mechanism. Paradoxically, although DnaK increases 39-mer binding, the increase was also achieved by inactivating the DnaK binding site of RctB. This result suggests that the site inhibits the 39-mer binding domain (via autoinhibition) when prevented from binding DnaK. Taken together, our results reveal an important feature of the transition from plasmid to chromosome: the Chr2 initiator retains the plasmid-like dimerization domain and its control by chaperones but uses the chaperones in an unprecedented way to control the inhibitory 39-mer binding.IMPORTANCEThe capacity of proteins to undergo remodeling provides opportunities to control their function. However, remodeling remains a poorly understood aspect of the structure-function paradigm due to its dynamic nature. Here we have studied remodeling of the initiator of replication ofVibrio choleraeChr2 by the molecular chaperone, DnaK. We show that DnaK binds to a site on the Chr2 initiator (RctB) that promotes initiation by reducing the initiator’s propensity to dimerize. Dimerization of the initiator of the putative plasmid progenitor of Chr2 is also reduced by DnaK, which promotes initiation. Paradoxically, the DnaK binding also promotes replication inhibition by reducing an autoinhibitory activity of RctB. In the plasmid-to-chromosome transition, it appears that the initiator has acquired an autoinhibitory activity and along with it a new chaperone activity that apparently helps to control replication inhibition independently of replication promotion.


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