Design Considerations for a Minimally Invasive High-Throughput Automation System for Radiation Biodosimetry

2007 ◽  
Author(s):  
A. Salerno ◽  
J. Zhang ◽  
A. Bhatla ◽  
O. V. Lyulko ◽  
J. Nie ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
High Throughput ◽  
Automation System ◽  
Design Considerations ◽  
Radiation Biodosimetry

scholarly journals Automated Analytical Measurement Processes Using a Dual-Arm Robotic System

2019 ◽  
Vol 24 (3) ◽  
pp. 354-356
Author(s):  
Heidi Fleischer ◽  
Shalaka Joshi ◽  
Thomas Roddelkopf ◽  
Michael Klos ◽  
Kerstin Thurow
Keyword(s):  
High Throughput ◽  
High Content Screening ◽  
Automation System ◽  
Analytical Measurement ◽  
Flexible Robots ◽  
Liquid Handling ◽  
Human Operators ◽  
Dual Arm Robot ◽  
Dual Arm ◽  
Direct Sample

The demand for automation in the analytical laboratory is high. In contrast to well-automated bioscreening and high-throughput and high-content screening processes, analytical measurement procedures are complex in their structure and changing frequently. Not only do robotic units have to perform transportation or specific single tasks, but also flexible robots are needed to cover several tasks, including transportation and direct sample manipulation. Due to their human-like structure, dual-arm robots are predestined for analytical measurement processes. A new study published in the journal Energies presents a novel integration of electronic piston pipettes into an automation system using a dual-arm robot to perform liquid handling tasks similar to human operators. In this commentary, the main findings are highlighted and discussed.

VALIDATING HIGH-THROUGHPUT MICRONUCLEUS ANALYSIS OF PERIPHERAL RETICULOCYTES FOR RADIATION BIODOSIMETRY: BENCHMARK AGAINST DICENTRIC AND CBMN ASSAYS IN A MOUSE MODEL

2010 ◽  
Vol 98 (2) ◽  
pp. 218-227 ◽  
Author(s):  
Yuhchyau Chen ◽  
Ying Tsai ◽  
Irena Nowak ◽  
Nancy Wang ◽  
Ollivier Hyrien ◽  
...  
Keyword(s):  
Mouse Model ◽  
High Throughput ◽  
Radiation Biodosimetry

scholarly journals Design and Preliminary Validation of a Rapid Automated Biodosimetry Tool for High Throughput Radiological Triage

2009 ◽  
Author(s):  
Youhua Chen ◽  
Jian Zhang ◽  
Hongliang Wang ◽  
Guy Garty ◽  
Yanping Xu ◽  
...  
Keyword(s):  
High Throughput ◽  
Parameter Determination ◽  
Automation System ◽  
Prototype System ◽  
Real Time Control ◽  
Time Control ◽  
Novel Approach ◽  
Concentration Estimation ◽  
Preliminary Validation ◽  
Control Versus

This paper presents design, hardware, software, and parameter optimization for a novel robotic automation system. RABiT is a Rapid Automated Biodosimetry Tool for high throughput radiological triage. The design considerations guiding the hardware and software architecture are presented with focus on methods of communication, ease of implementation, and need for real-time control versus soft time control cycles. The design and parameter determination for a non-contact PVC capillary laser cutting system is presented. A novel approach for lymphocyte concentration estimation based on computer vision is reported. Experimental evaluations of the system components validate the success of our prototype system in achieving a throughput of 6,000 samples in a period of 18 hours.

scholarly journals Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay

2019 ◽  
Vol 191 (4) ◽  
pp. 342 ◽  
Author(s):  
Qi Wang ◽  
Matthew A. Rodrigues ◽  
Mikhail Repin ◽  
Sergey Pampou ◽  
Lindsay A. Beaton-Green ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
High Throughput ◽  
Micronucleus Assay ◽  
Imaging Flow Cytometry ◽  
Radiation Biodosimetry
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