Design Approach for Parameter Estimators for One-parameter First-order Scalar Plant

Author(s):  
Arnab Das ◽  
Bipa Datta ◽  
Achintya Das
1997 ◽  
Vol 34 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Mohamad Adnan Al-Alaoui

A class of stable, first order, s-to-z transforms is presented. The transforms are obtained by interpolating the traditional trapezoidal and rectangular integration rules. An interactive design approach is introduced by varying one parameter. The sampling rate would be another parameter that may be varied to obtain the lowest sampling rate for the desired response.


Author(s):  
Kulkarni Manasi B ◽  
Joshi Anagha M

Objective: The aim of the present work is to use experimental design to screen and optimize experimental variables for developing a colorimetric first-order derivative method for determining content of serralysin (SER) using biuret and Folin–Ciocalteu phenol reagent for stable color development. The method is based on the reaction of peptide bond in the protein with Biuret reagent in alkaline medium and further reaction of remaining tryptophan and tyrosine residues with Folin–Ciocalteu Phenol reagent to form a stable blue-colored complex (first-order derivative λmax 620 nm).Materials and Methods: A two-level full factorial design was utilized to screen the effect of Volume of NaOH (A), volume of biuret reagent (B), volume of Folin–Ciocalteu phenol reagent (C), and concentration of NaOH (D) on the formation of blue-colored SER - reagent complex (response - absorbance). A box Behnken experimental design with response surface methodology was then utilized to evaluate the main interaction and quadratic effects of these factors on the selected response.Results: With the help of a response surface plot and contour plot, the optimum values of the selected factors were determined and used for further experiments. These values were volume of NaOH (A) of 1.0 mL, volume of biuret reagent (B) of 0.25 mL, and volume of Folin–Ciocalteu phenol reagent (C) of 10 μL. The proposed method was validated according to the ICH Q2(R1) method validation guidelines. The developed colorimetric first-order derivative method was found to be simple, accurate, rapid, sensitive, precise, and economic. Further optimization of the method with experimental design approach makes it convenient for use in laboratory.Conclusion: The results of present study have clearly shown that an experimental design approach may be effectively applied to the optimization of a modified visible spectrophotometric method for estimation of SER in bulk and in pharmaceutical formulation with the least number of experimental runs possible. The method can be employed successfully for the estimation of SER in both bulk and tablet dosage form. 


1995 ◽  
Vol 29 (5) ◽  
pp. 1343-1351 ◽  
Author(s):  
K.V. Ellis ◽  
P.C. Rodrigues

2019 ◽  
Vol 42 ◽  
Author(s):  
Daniel J. Povinelli ◽  
Gabrielle C. Glorioso ◽  
Shannon L. Kuznar ◽  
Mateja Pavlic

Abstract Hoerl and McCormack demonstrate that although animals possess a sophisticated temporal updating system, there is no evidence that they also possess a temporal reasoning system. This important case study is directly related to the broader claim that although animals are manifestly capable of first-order (perceptually-based) relational reasoning, they lack the capacity for higher-order, role-based relational reasoning. We argue this distinction applies to all domains of cognition.


1984 ◽  
Vol 75 ◽  
pp. 461-469 ◽  
Author(s):  
Robert W. Hart

ABSTRACTThis paper models maximum entropy configurations of idealized gravitational ring systems. Such configurations are of interest because systems generally evolve toward an ultimate state of maximum randomness. For simplicity, attention is confined to ultimate states for which interparticle interactions are no longer of first order importance. The planets, in their orbits about the sun, are one example of such a ring system. The extent to which the present approximation yields insight into ring systems such as Saturn's is explored briefly.


Author(s):  
Richard J. Spontak ◽  
Steven D. Smith ◽  
Arman Ashraf

Block copolymers are composed of sequences of dissimilar chemical moieties covalently bonded together. If the block lengths of each component are sufficiently long and the blocks are thermodynamically incompatible, these materials are capable of undergoing microphase separation, a weak first-order phase transition which results in the formation of an ordered microstructural network. Most efforts designed to elucidate the phase and configurational behavior in these copolymers have focused on the simple AB and ABA designs. Few studies have thus far targeted the perfectly-alternating multiblock (AB)n architecture. In this work, two series of neat (AB)n copolymers have been synthesized from styrene and isoprene monomers at a composition of 50 wt% polystyrene (PS). In Set I, the total molecular weight is held constant while the number of AB block pairs (n) is increased from one to four (which results in shorter blocks). Set II consists of materials in which the block lengths are held constant and n is varied again from one to four (which results in longer chains). Transmission electron microscopy (TEM) has been employed here to investigate the morphologies and phase behavior of these materials and their blends.


1991 ◽  
Vol 3 (1) ◽  
pp. 235-253 ◽  
Author(s):  
L. D. Philipp ◽  
Q. H. Nguyen ◽  
D. D. Derkacht ◽  
D. J. Lynch ◽  
A. Mahmood

Author(s):  
Julian M. Etzel ◽  
Gabriel Nagy

Abstract. In the current study, we examined the viability of a multidimensional conception of perceived person-environment (P-E) fit in higher education. We introduce an optimized 12-item measure that distinguishes between four content dimensions of perceived P-E fit: interest-contents (I-C) fit, needs-supplies (N-S) fit, demands-abilities (D-A) fit, and values-culture (V-C) fit. The central aim of our study was to examine whether the relationships between different P-E fit dimensions and educational outcomes can be accounted for by a higher-order factor that captures the shared features of the four fit dimensions. Relying on a large sample of university students in Germany, we found that students distinguish between the proposed fit dimensions. The respective first-order factors shared a substantial proportion of variance and conformed to a higher-order factor model. Using a newly developed factor extension procedure, we found that the relationships between the first-order factors and most outcomes were not fully accounted for by the higher-order factor. Rather, with the exception of V-C fit, all specific P-E fit factors that represent the first-order factors’ unique variance showed reliable and theoretically plausible relationships with different outcomes. These findings support the viability of a multidimensional conceptualization of P-E fit and the validity of our adapted instrument.


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