scholarly journals Dual Skip Connections Minimize the False Positive Rate of Lung Nodule Detection in CT images

Author(s):  
Jiahua Xu ◽  
Philipp Ernst ◽  
Tung Lung Liu ◽  
Andreas Nurnberger
2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Panpan Wu ◽  
Xuanchao Sun ◽  
Ziping Zhao ◽  
Haishuai Wang ◽  
Shirui Pan ◽  
...  

The classification process of lung nodule detection in a traditional computer-aided detection (CAD) system is complex, and the classification result is heavily dependent on the performance of each step in lung nodule detection, causing low classification accuracy and high false positive rate. In order to alleviate these issues, a lung nodule classification method based on a deep residual network is proposed. Abandoning traditional image processing methods and taking the 50-layer ResNet network structure as the initial model, the deep residual network is constructed by combining residual learning and migration learning. The proposed approach is verified by conducting experiments on the lung computed tomography (CT) images from the publicly available LIDC-IDRI database. An average accuracy of 98.23% and a false positive rate of 1.65% are obtained based on the ten-fold cross-validation method. Compared with the conventional support vector machine (SVM)-based CAD system, the accuracy of our method improved by 9.96% and the false positive rate decreased by 6.95%, while the accuracy improved by 1.75% and 2.42%, respectively, and the false positive rate decreased by 2.07% and 2.22%, respectively, in contrast to the VGG19 model and InceptionV3 convolutional neural networks. The experimental results demonstrate the effectiveness of our proposed method in lung nodule classification for CT images.


Author(s):  
Xiaoqi Lu ◽  
Yu Gu ◽  
Lidong Yang ◽  
Baohua Zhang ◽  
Ying Zhao ◽  
...  

Objective: False-positive nodule reduction is a crucial part of a computer-aided detection (CADe) system, which assists radiologists in accurate lung nodule detection. In this research, a novel scheme using multi-level 3D DenseNet framework is proposed to implement false-positive nodule reduction task. Methods: Multi-level 3D DenseNet models were extended to differentiate lung nodules from falsepositive nodules. First, different models were fed with 3D cubes with different sizes for encoding multi-level contextual information to meet the challenges of the large variations of lung nodules. In addition, image rotation and flipping were utilized to upsample positive samples which consisted of a positive sample set. Furthermore, the 3D DenseNets were designed to keep low-level information of nodules, as densely connected structures in DenseNet can reuse features of lung nodules and then boost feature propagation. Finally, the optimal weighted linear combination of all model scores obtained the best classification result in this research. Results: The proposed method was evaluated with LUNA16 dataset which contained 888 thin-slice CT scans. The performance was validated via 10-fold cross-validation. Both the Free-response Receiver Operating Characteristic (FROC) curve and the Competition Performance Metric (CPM) score show that the proposed scheme can achieve a satisfactory detection performance in the falsepositive reduction track of the LUNA16 challenge. Conclusion: The result shows that the proposed scheme can be significant for false-positive nodule reduction task.


Author(s):  
Furqan SHAUKAT ◽  
Kamran JAVED ◽  
Gulistan RAJA ◽  
Junaid MIR ◽  
Muhammad Laiq Ur Rahman SHAHID

2011 ◽  
Vol 38 (10) ◽  
pp. 5630-5645 ◽  
Author(s):  
Maxine Tan ◽  
Rudi Deklerck ◽  
Bart Jansen ◽  
Michel Bister ◽  
Jan Cornelis

Sign in / Sign up

Export Citation Format

Share Document