A new scheme for the automatic assessment of Alzheimer’s disease on a fine motor task with Transfer Learning*

Author(s):  
M. Kachouri ◽  
N. Houmani ◽  
S. Garcia-Salicetti ◽  
A.-S. Rigaud
Author(s):  
Nicole Dalia Cilia ◽  
Claudio De Stefano ◽  
Claudio Marrocco ◽  
Francesco Fontanella ◽  
Mario Molinara ◽  
...  

Author(s):  
Atif Mehmood ◽  
Shuyuan yang ◽  
Zhixi feng ◽  
Min wang ◽  
AL Smadi Ahmad ◽  
...  

2014 ◽  
Vol 39 (1) ◽  
pp. 291-296 ◽  
Author(s):  
Joanne E. Wittwer ◽  
Kate E. Webster ◽  
Keith Hill

2019 ◽  
Vol 6 (4) ◽  
pp. 209-216
Author(s):  
Deekshitha Prakash ◽  
Nuwan Madusanka ◽  
Subrata Bhattacharjee ◽  
Hyeon-Gyun Park ◽  
Cho-Hee Kim ◽  
...  

2021 ◽  
Author(s):  
Sydney Y Schaefer ◽  
Michael Malek-Ahmadi ◽  
Andrew Hooyman ◽  
Jace B. King ◽  
Kevin Duff

Hippocampal atrophy is a widely used biomarker for Alzheimer's disease (AD), but the cost, time, and contraindications associated with magnetic resonance imaging (MRI) limit its use. Recent work has shown that a low-cost upper extremity motor task has potential in identifying AD risk. Fifty-four older adults (15 cognitively unimpaired, 24 amnestic Mild Cognitive Impairment, and 15 AD) completed six motor task trials and a structural MRI. Motor task acquisition significantly predicted bilateral hippocampal volume, controlling for age, sex, education, and memory. Thus, this motor task may be an affordable, non-invasive screen for AD risk and progression.


Sensors ◽  
2019 ◽  
Vol 19 (11) ◽  
pp. 2645 ◽  
Author(s):  
Muazzam Maqsood ◽  
Faria Nazir ◽  
Umair Khan ◽  
Farhan Aadil ◽  
Habibullah Jamal ◽  
...  

Alzheimer’s disease effects human brain cells and results in dementia. The gradual deterioration of the brain cells results in disability of performing daily routine tasks. The treatment for this disease is still not mature enough. However, its early diagnosis may allow restraining the spread of disease. For early detection of Alzheimer’s through brain Magnetic Resonance Imaging (MRI), an automated detection and classification system needs to be developed that can detect and classify the subject having dementia. These systems also need not only to classify dementia patients but to also identify the four progressing stages of dementia. The proposed system works on an efficient technique of utilizing transfer learning to classify the images by fine-tuning a pre-trained convolutional network, AlexNet. The architecture is trained and tested over the pre-processed segmented (Grey Matter, White Matter, and Cerebral Spinal Fluid) and un-segmented images for both binary and multi-class classification. The performance of the proposed system is evaluated over Open Access Series of Imaging Studies (OASIS) dataset. The algorithm showed promising results by giving the best overall accuracy of 92.85% for multi-class classification of un-segmented images.


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