Preictal onset detection through unsupervised clustering for epileptic seizure prediction

Epilepsy is one of the most common neurological disorders, which is characterized by unpredictable brain seizure. About 30% of the patients are not even aware that they have epilepsy and many have to undergo surgeries to relieve the pain. Therefore, developing a robust brain-computer interface for seizure prediction can help epileptic patients significantly. In this paper, we propose a hybrid CNN-SVM model for better epileptic seizure prediction. A convolutional neural network (CNN) consists of a multilayer structure, which can be adapted and modified according to the requirement of different applications. A support vector machine is a discriminative classifier which can be described by a separating optimal hyperplane used for categorizing new samples. The combination of CNN and SVM is found to provide an effective way for epileptic prediction. Furthermore, the resulting model is made autonomous using edge computing services and is shown to be a viable seizure prediction method. The results can be beneficial in real-life support of epilepsy patients.

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A Novel Permutation Entropy-Based EEG Channel Selection for Improving Epileptic Seizure Prediction

Sensors ◽

10.3390/s21237972 ◽

2021 ◽

Vol 21 (23) ◽

pp. 7972

Author(s):

Jee S. Ra ◽

Tianning Li ◽

Yan Li

Keyword(s):

Sensitivity And Specificity ◽

Epileptic Seizure ◽

Epileptic Seizures ◽

Optimization Method ◽

Channel Selection ◽

Permutation Entropy ◽

Patient Specific ◽

Support Vector ◽

Seizure Prediction ◽

Epileptic Seizure Prediction

The key research aspects of detecting and predicting epileptic seizures using electroencephalography (EEG) signals are feature extraction and classification. This paper aims to develop a highly effective and accurate algorithm for seizure prediction. Efficient channel selection could be one of the solutions as it can decrease the computational loading significantly. In this research, we present a patient-specific optimization method for EEG channel selection based on permutation entropy (PE) values, employing K nearest neighbors (KNNs) combined with a genetic algorithm (GA) for epileptic seizure prediction. The classifier is the well-known support vector machine (SVM), and the CHB-MIT Scalp EEG Database is used in this research. The classification results from 22 patients using the channels selected to the patient show a high prediction rate (average 92.42%) compared to the SVM testing results with all channels (71.13%). On average, the accuracy, sensitivity, and specificity with selected channels are improved by 10.58%, 23.57%, and 5.56%, respectively. In addition, four patient cases validate over 90% accuracy, sensitivity, and specificity rates with just a few selected channels. The corresponding standard deviations are also smaller than those used by all channels, demonstrating that tailored channels are a robust way to optimize the seizure prediction.

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