Development of a cross flow filtration device for human blood cell fractionation

Author(s):  
Divyagash Swargaloganathan
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiersten D. Lenz ◽  
Shailja Jakhar ◽  
Jing W. Chen ◽  
Aaron S. Anderson ◽  
Dylan C. Purcell ◽  
...  

AbstractThe separation of biomarkers from blood is straightforward in most molecular biology laboratories. However, separation in resource-limited settings, allowing for the successful removal of biomarkers for diagnostic applications, is not always possible. The situation is further complicated by the need to separate hydrophobic signatures such as lipids from blood. Herein, we present a microfluidic device capable of centrifugal separation of serum from blood at the point of need with a system that is compatible with biomarkers that are both hydrophilic and hydrophobic. The cross-flow filtration device separates serum from blood as efficiently as traditional methods and retains amphiphilic biomarkers in serum for detection.


2018 ◽  
Vol 257 ◽  
pp. 924-930 ◽  
Author(s):  
R. Lanfranco ◽  
J. Saez ◽  
E. Di Nicolò ◽  
F. Benito-Lopez ◽  
M. Buscaglia

2009 ◽  
Vol 59 (S2) ◽  
pp. 189-191
Author(s):  
V. Hames ◽  
L. Berthe-Corti ◽  
M. Focken ◽  
M. Nachtkamp ◽  
E. Diel ◽  
...  

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