Cross-flow filtration device with filtrate conduit network and method of making same

2001 ◽  
Vol 38 (2) ◽  
pp. 16
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiersten D. Lenz ◽  
Shailja Jakhar ◽  
Jing W. Chen ◽  
Aaron S. Anderson ◽  
Dylan C. Purcell ◽  
...  

AbstractThe separation of biomarkers from blood is straightforward in most molecular biology laboratories. However, separation in resource-limited settings, allowing for the successful removal of biomarkers for diagnostic applications, is not always possible. The situation is further complicated by the need to separate hydrophobic signatures such as lipids from blood. Herein, we present a microfluidic device capable of centrifugal separation of serum from blood at the point of need with a system that is compatible with biomarkers that are both hydrophilic and hydrophobic. The cross-flow filtration device separates serum from blood as efficiently as traditional methods and retains amphiphilic biomarkers in serum for detection.


2018 ◽  
Vol 257 ◽  
pp. 924-930 ◽  
Author(s):  
R. Lanfranco ◽  
J. Saez ◽  
E. Di Nicolò ◽  
F. Benito-Lopez ◽  
M. Buscaglia

1992 ◽  
Vol 25 (10) ◽  
pp. 319-327 ◽  
Author(s):  
P. D. Rose ◽  
B. A. Maart ◽  
T. D. Phillips ◽  
S. L. Tucker ◽  
A. K. Cowan ◽  
...  

An algal high rate oxidation ponding process for treating organic s present in saline effluents has been described. The extreme halophile Dunaliella salina can be made to predominate in the system by manipulating salinity, producing products of value together with a waste treatment function. Application in treating tannery saline organic wastes was examined. Techniques appropriate for the harvesting of micro-algae from this and other algal production systems presents a limiting factor in the development of algal biotechnology. Cross-flow filtration was evaluated as a technique for micro-algal cell separation. Both microfiltration and ultrafiltration were found to produce effective algal removal from the medium, Cross-flow ultrafiltration with a polyethersulfone coated tubular filter produced effective separation with the production of cell concentrates in a viable condition. Flux rates of 30 - 40 LMH fall within acceptable levels for application in industrial processes. Cell shattering observed with microfiltration precludes its use for recovering whole or viable cell concentrates.


1991 ◽  
Vol 37 (3) ◽  
pp. 215-222 ◽  
Author(s):  
Kazuaki Yamagiwa ◽  
Yoshikazu Ohmae ◽  
M. Hatta Dahlan ◽  
Akira Ohkawa

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