Assessment of cortical inhibition in adult attention-deficit/hyperactivity disorder by paired-chirp auditory evoked potentials

Author(s):  
Ernesto Gonzalez-Trejo ◽  
Florence Philipp-Wiegmann ◽  
Konstanze D. Romer ◽  
Philip Reinert ◽  
Yin Fen Low ◽  
...  
2012 ◽  
Vol 262 (6) ◽  
pp. 507-517 ◽  
Author(s):  
Wolfgang Retz ◽  
Ernesto González-Trejo ◽  
Konstanze D. Römer ◽  
Florence Philipp-Wiegmann ◽  
Philip Reinert ◽  
...  

2014 ◽  
Vol 28 (2) ◽  
pp. 63-72
Author(s):  
Bo-Kyung Seo ◽  
Gudrun Sartory ◽  
Bernhard Kis ◽  
Norbert Scherbaum ◽  
Bernhard W. Müller

Intensity-dependent auditory evoked potentials (IDAP) were shown to be increased in highly impulsive individuals. As impulsivity is one of the core symptoms of attention deficit/hyperactivity disorder (ADHD), patients with ADHD were expected to exhibit an enhanced IDAP. Twenty-five ADHD patients taking methylphenidate and 21 healthy control participants were given diagnostic questionnaires including the Barratt Impulsivity Scale and IDAP was assessed with five-tone intensities. Amplitude, latency, and intensity slope of the N1, P2, and N1/P2 were determined. Contrary to our hypothesis, there was no significant group difference with regard to N1 amplitude and ADHD patients exhibited significantly lower P2 amplitude at high intensity and a flatter N1/P2 slope of the stimulus intensity function than healthy controls. Motor impulsivity, a subscale of the Barratt impulsivity scale, showed a significantly negative correlation with P2 amplitude within the ADHD group. The unexpected results could be due to the effect of methylphenidate.


2007 ◽  
Vol 118 (6) ◽  
pp. 1286-1290 ◽  
Author(s):  
Masahito Miyazaki ◽  
Emiko Fujii ◽  
Takahiko Saijo ◽  
Kenji Mori ◽  
Shoji Kagami

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