Scintillation Detector Design Study for Prompt Gamma Photon Detection in Proton Therapy Monitoring

2017 ◽  
Author(s):  
Hongyang Zhang ◽  
Peng Fan ◽  
Tianpeng Xu ◽  
Qingyang Wei ◽  
Tianyu Ma ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Scintillation Detector ◽  
Therapy Monitoring ◽  
Prompt Gamma ◽  
Gamma Photon ◽  
Design Study ◽  
Photon Detection ◽  
Detector Design

scholarly journals Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring

2016 ◽  
Vol 6 ◽  
Author(s):  
Marco Pinto ◽  
Denis Dauvergne ◽  
Nicolas Freud ◽  
Jochen Krimmer ◽  
Jean M. Létang ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Therapy Monitoring ◽  
Prompt Gamma ◽  
Gamma Emission

scholarly journals OC-0557: Implementation and validation of an analytical model for prompt gamma imaging in scanned beam proton therapy

2015 ◽  
Vol 115 ◽  
pp. S271-S272
Author(s):  
E. Sterpin ◽  
G. Janssens ◽  
J. Smeets ◽  
F. Vander Stappen ◽  
D. Prieels ◽  
...  
Keyword(s):  
Analytical Model ◽  
Proton Therapy ◽  
Prompt Gamma ◽  
Gamma Imaging ◽  
Beam Proton ◽  
Prompt Gamma Imaging

scholarly journals Metallic Nanoparticles: A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy?

Radiation ◽  
2021 ◽  
Vol 1 (4) ◽  
pp. 305-316
Author(s):  
Sébastien Penninckx ◽  
Félicien Hespeels ◽  
Julien Smeets ◽  
Julien L. Colaux ◽  
Stéphane Lucas ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Metallic Nanoparticles ◽  
Target Volume ◽  
Prompt Gamma ◽  
Dose Delivery ◽  
Non Invasive ◽  
Safety Margins ◽  
Medical Physicists ◽  
Invasive Techniques ◽  
Therapy Treatment

In clinical practice, dose delivery in proton therapy treatment is affected by uncertainties related to the range of the beam in the patient, which requires medical physicists to introduce safety margins on the penetration depth of the beam. Although this ensures an irradiation of the entire clinical target volume with the prescribed dose, these safety margins also lead to the exposure of nearby healthy tissues and a subsequent risk of side effects. Therefore, non-invasive techniques that allow for margin reduction through online monitoring of prompt gammas emitted along the proton tracks in the patient are currently under development. This study provides the proof-of-concept of metal-based nanoparticles, injected into the tumor, as a prompt gamma enhancer, helping in the beam range verification. It identifies the limitations of this application, suggesting a low feasibility in a realistic clinical scenario but opens some avenues for improvement.

Measuring prompt gamma-ray emissions from elements found in tissue during passive-beam proton therapy

2021 ◽  
Vol 7 (2) ◽  
pp. 025013
Author(s):  
Jeyasingam Jeyasugiththan ◽  
Jaime Nieto Camero ◽  
Julyan Symons ◽  
Pete Jones ◽  
Andy Buffler ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Gamma Ray ◽  
Prompt Gamma ◽  
Beam Proton
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