With the build of Monitoring Center in our country, a great of signals are uploaded from many substations which are located on every corner. When an abnormal or a grid fault in Power System happens, lots of signals come out, then many operators on duty can’t often react quickly and judge the fault accurately.Recently,more and more scholars begin studying intelligent alarm processing system. In this paper, by analyzing signals characters and SCADA network of Monitoring Center, an intelligent processing frame to alarms in monitoring center is provided, the frame includes three layers named signals foundation treatment layer, signals connecting and sharing layer, signals intelligent diagnosis layer. Now the frame has been implemented successfully in Monitoring Center of our company. At the same time, based on an virtual signals software, lots of devices alarms and grid faults are simulated, this intelligent processing system, which are built on the frame, always show the alarm tip quickly. Facts prove it attributes to grid fault judge for operators of Monitoring Center.