PUPy: A Generalized, Optimistic Context Detection Framework for Implicit Authentication

Author(s):  
Matthew Rafuse ◽  
Urs Hengartner
Keyword(s):  
Author(s):  
Kartik Sankaran ◽  
Minhui Zhu ◽  
Xiang Fa Guo ◽  
Akkihebbal L. Ananda ◽  
Mun Choon Chan ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1296 ◽  
Author(s):  
Enrico Cadoni ◽  
Alex Manicardi ◽  
Annemieke Madder

MicroRNAs (miRNAs or miRs) are small noncoding RNAs involved in the fine regulation of post-transcriptional processes in the cell. The physiological levels of these short (20–22-mer) oligonucleotides are important for the homeostasis of the organism, and therefore dysregulation can lead to the onset of cancer and other pathologies. Their importance as biomarkers is constantly growing and, in this context, detection methods based on the hybridization to peptide nucleic acids (PNAs) are gaining their place in the spotlight. After a brief overview of their biogenesis, this review will discuss the significance of targeting miR, providing a wide range of PNA-based approaches to detect them at biologically significant concentrations, based on electrochemical, fluorescence and colorimetric assays.


2016 ◽  
Author(s):  
Pujitha Mannaru ◽  
Balakumar Balasingam ◽  
Krishna Pattipati ◽  
Ciara Sibley ◽  
Joseph Coyne

2017 ◽  
Vol 6 (2) ◽  
pp. 1539
Author(s):  
A. R. Shashikiran ◽  
Nadiga Rajashekhar

"Dyssebacia" is the name coined to describe numerous plugs of inspissated sebum projecting from dilated orifices of sebaceous glands. This is a case series report of 12 patients who presented to our department with complaints of asymptomatic skin lesions which started first in lower part of nose followed by involvement of entire nose, cheeks and forehead .On examination there were multiple yellow plugs of sebum projecting out from follicular orifices resembling those of shark skin. Dermoscopic examination and Urinary levels of Niacinamide levels in urine were estimated in few cases. Based on history, clinical examination and laboratory, Diagnosis of dyssebacia was made and patients were started on niacinamide following which there was improvement in lesions in 8 of the 12 patients within two to four weeks. Diagnosis of pellagra is based on clinical criteria. Dyssebacia can be the early cutaneous marker of niacin deficiency. Thus in this context detection of dyssebecia acts as a primeval marker in diagnosis of pellagra, which still exists in epidemic proportions in many countries.


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