Modeling Of Intracranial Pressure Dynamics

2005 ◽  
Author(s):  
R.L. Griffith ◽  
H.G. Sullivan ◽  
J.D. Miller
Keyword(s):  
Intracranial Pressure ◽  
Pressure Dynamics

Raised intracranial pressure, cerebral oedema, and hydrocephalus

2011 ◽  
Author(s):  
Ian Whittle
Keyword(s):  
Intracranial Pressure ◽  
Dynamic Equilibrium ◽  
Venous Pressure ◽  
Venous Blood ◽  
Contributory Factor ◽  
Common Disease ◽  
Brain Vessels ◽  
Arterial Blood ◽  
Pressure Dynamics ◽  
The Brain

The brain is protected by the cranial skeleton. Within the intracranial compartment are also cerebrospinal fluid, CSF, and the blood contained within the brain vessels. These intracranial components are in dynamic equilibrium due to the pulsations of the heart and the respiratory regulated return of venous blood from the brain. Normally the mean arterial blood pressure, systemic venous pressure, and brain volume are regulated to maintain physiological values for intracranial pressure, ICP. There are a range of very common disorders such as stroke, and much less common, such as idiopathic intracranial hypertension, that are associated with major disturbances of intracranial pressure dynamics. In some of these the contribution to pathophysiology is relatively minor whereas in others it may be substantial and be a major contributory factor to morbidity or even death.Intracranial pressure can be disordered because of brain oedema, disturbances in CSF flow, mass lesions, and vascular engorgement of the brain. Each of these may have variable causes and there may be interactions between mechanisms. In this chapter the normal regulation of intracranial pressure is outlined and some common disease states in clinical neurological practice that are characterized by either primary or secondary problems in intracranial pressure dynamics described.

scholarly journals Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis

2020 ◽  
Vol 2 (8) ◽  
pp. e0197 ◽  
Author(s):  
Teodor Svedung Wettervik ◽  
Eva Kumlien ◽  
Elham Rostami ◽  
Timothy Howells ◽  
Magnus von Seth ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Vasomotor Reactivity ◽  
Acute Encephalitis ◽  
Cerebral Vasomotor Reactivity ◽  
Pressure Dynamics

POSTOPERATIVE HYDROCEPHALUS IN PATIENTS UNDERGOING DECOMPRESSIVE HEMICRANIECTOMY FOR ISCHEMIC OR HEMORRHAGIC STROKE

Neurosurgery ◽  
2007 ◽  
Vol 61 (3) ◽  
pp. 489-494 ◽  
Author(s):  
Allen Waziri ◽  
David Fusco ◽  
Stephan A. Mayer ◽  
Guy M. McKhann ◽  
E. Sander Connolly
Keyword(s):  
Intracranial Pressure ◽  
Hemorrhagic Stroke ◽  
Communicating Hydrocephalus ◽  
Imaging Data ◽  
Decompressive Hemicraniectomy ◽  
Pressure Dynamics ◽  
Csf Diversion ◽  
Postoperative Hydrocephalus ◽  
Early Cranioplasty ◽  
Persistent Hydrocephalus

Abstract OBJECTIVE We have frequently observed the development of postoperative communicating hydrocephalus in patients undergoing decompressive hemicraniectomy. This condition may persist in some patients after cranioplasty and require permanent cerebrospinal fluid (CSF) diversion. To confirm an independent correlation between hemicraniectomy and the development of communicating hydrocephalus, and to detail the frequency and potential clinical factors contributing to this complication, we evaluated our series of patients undergoing hemicraniectomy for life-threatening increases in intracranial pressure secondary to ischemic or hemorrhagic stroke. METHODS A retrospective analysis was performed with a cohort of consecutive patients who underwent emergent hemicraniectomy for medically refractory elevations in intracranial pressure. Patients with known independent risk factors for the development of communicating hydrocephalus were excluded. Clinical and imaging data were reviewed to determine the incidence and type of hydrocephalus after hemicraniectomy, the persistence of hydrocephalus after cranioplasty, and the need for permanent CSF diversion. RESULTS Eighty-eight percent of the eligible patients undergoing hemicraniectomy in our cohort developed postoperative communicating hydrocephalus. Half of these patients harbored persistent hydrocephalus after cranioplasty and required placement of a ventriculoperitoneal shunt. We noted a strong correlation between prolonged time to replacement of the bone flap and persistence of hydrocephalus. CONCLUSION Communicating hydrocephalus is an almost universal finding in patients after hemicraniectomy. Delayed time to cranioplasty is linked with the development of persistent hydrocephalus, necessitating permanent CSF diversion in some patients. We propose that early cranioplasty, when possible, may restore normal intracranial pressure dynamics and prevent the need for permanent CSF diversion in patients after hemicraniectomy.

Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Teodor M. Svedung Wettervik ◽  
Henrik Engquist ◽  
Samuel Lenell ◽  
Timothy Howells ◽  
Lars Hillered ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Energy Metabolism ◽  
Intracranial Pressure ◽  
Clinical Outcome ◽  
Cerebral Energy Metabolism ◽  
Pressure Dynamics

Intracranial pressure dynamics in clinical practice: online PC-based ICP monitoring system

1994 ◽  
Vol 32 (5) ◽  
pp. 512-520 ◽  
Author(s):  
M. A. Gonzalez ◽  
M. A. Quiles ◽  
N. Pulido ◽  
R. Garcia-Sola ◽  
C. H. Salvador
Keyword(s):  
Clinical Practice ◽  
Intracranial Pressure ◽  
Monitoring System ◽  
Icp Monitoring ◽  
Pressure Dynamics

Intracranial Pressure Dynamics During Head Impact

1977 ◽  
Author(s):  
Alan M. Nahum ◽  
Randall Smith ◽  
Carley C. Ward
Keyword(s):  
Intracranial Pressure ◽  
Head Impact ◽  
Pressure Dynamics

scholarly journals Intracranial pressure dynamics in patients with acute brain damage

1997 ◽  
Vol 82 (4) ◽  
pp. 1270-1282 ◽  
Author(s):  
M. Ursino ◽  
C. A. Lodi ◽  
S. Rossi ◽  
N. Stocchetti
Keyword(s):  
Intracranial Pressure ◽  
Brain Damage ◽  
Blood Volume ◽  
Time Constant ◽  
Cerebral Blood Volume ◽  
Volume Index ◽  
Parameter Estimates ◽  
Time Pattern ◽  
Pressure Dynamics ◽  
Parameter Values

Ursino, M., C. A. Lodi, S. Rossi, and N. Stocchetti.Intracranial pressure dynamics in patients with acute brain damage. J. Appl. Physiol. 82(4): 1270–1282, 1997.—The time pattern of intracranial pressure (ICP) during pressure-volume index (PVI) tests was analyzed in 20 patients with severe acute brain damage by means of a simple mathematical model. In most cases, a satisfactory fitting between model response and patient data was achieved by adjusting only four parameters: the cerebrospinal fluid (CSF) outflow resistance, the intracranial elastance coefficient, and the gain and time constant of cerebral autoregulation. The correlation between the parameter estimates was also analyzed to elucidate the main mechanisms responsible for ICP changes in each patient. Starting from information on the estimated parameter values and their correlation, the patients were classified into two main classes: those with weak autoregulation (8 of 20 patients) and those with strong autoregulation (12 of 20 patients). In the first group of patients, ICP mainly reflects CSF circulation and passive cerebral blood volume changes. In the second group, ICP exhibits paradoxical responses attributable to active changes in cerebral blood volume. Moreover, in two patients of the second group, the time constant of autoregulation is significantly increased (>40 s). The correlation between the parameter estimates was significantly different in the two groups of patients, suggesting the existence of different mechanisms responsible for ICP changes. Moreover, analysis of the correlation between the parameter estimates might give information on the directions of parameter changes that have a greater impact on ICP.

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