scholarly journals A Multiscale Tridomain Model for Simulating Bioelectric Gastric Pacing

2015 ◽  
Vol 62 (11) ◽  
pp. 2685-2692 ◽  
Author(s):  
Shameer Sathar ◽  
Mark L. Trew ◽  
Greg O'Grady ◽  
Leo K. Cheng
Keyword(s):  
Gastric Pacing

Design and validation of a surface-contact electrode for gastric pacing and concurrent slow-wave mapping

2021 ◽  
pp. 1-1
Author(s):  
Saeed Alighaleh ◽  
Leo K Cheng ◽  
Timothy R. Angeli ◽  
Zahra Aghababaie ◽  
Gregory O'Grady ◽  
...  
Keyword(s):  
Slow Wave ◽  
Gastric Pacing ◽  
Surface Contact ◽  
Contact Electrode

Feasibility of gastric pacing using pulse trains and effects of duty cycles

2003 ◽  
Vol 124 (4) ◽  
pp. A575
Author(s):  
Zhishun Wang ◽  
Lijie Wang ◽  
Xiaohong Xu ◽  
Jinsong Liu ◽  
Douglas Brining ◽  
...  
Keyword(s):  
Pulse Trains ◽  
Gastric Pacing ◽  
Duty Cycles

A Biophysically-Based Tissue Model for Optimizing Gastric Pacing

2014 ◽  
pp. 52-55
Author(s):  
S. Sathar ◽  
G. O’Grady ◽  
M. L. Trew ◽  
Leo K. Cheng
Keyword(s):  
Tissue Model ◽  
Gastric Pacing

Gastric Pacing

2017 ◽  
pp. 283-292
Author(s):  
Pratik S. Naik ◽  
Richard W. McCallum
Keyword(s):  
Gastric Pacing

Gastric pacing as a treatment for intractable gastroparesis: Shocking news?

1998 ◽  
Vol 114 (3) ◽  
pp. 598-601 ◽  
Author(s):  
Gervais Tougas ◽  
Jan D. Huizinga
Keyword(s):  
Gastric Pacing

Thermally Responsive Structures for Gastric Pacing and Other Applications

2010 ◽  
Author(s):  
Naga S. Korivi ◽  
Charles Halliburton ◽  
Pratul K. Ajmera
Keyword(s):  
Body Temperature ◽  
Solid Phase ◽  
Polymer Structure ◽  
Important Application ◽  
The Body ◽  
Channel Network ◽  
Gastric Pacing ◽  
Thermally Responsive ◽  
Responsive Polymer ◽  
Polymeric Layer

We report on the development of a polymeric layer consisting of an embedded channel network. The channels are filled with a thermally responsive polymer. The embedded thermally responsive polymer is in solid phase in room ambient, but changes to liquid at physiological body temperature (∼37 °C). This phase change results in the polymer structure changing to a more flexible state. An important application of this polymer layer is its use as a thermally regulated support structure for a gastric pacing electrode, to give some rigidity to the electrode body preferable during implantation surgery, while changing to a more flexible state inside the body as the embedded polymer subsequently melts at physiological temperature. The latter is expected to reduce complications caused by a rigid device.

Retrograde Gastric Pacing Reduces Food Intake and Delays Gastric Emptying in Humans: A Potential Therapy for Obesity?

2005 ◽  
Vol 50 (9) ◽  
pp. 1569-1575 ◽  
Author(s):  
Shukun Yao ◽  
Meiyun Ke ◽  
Zhifeng Wang ◽  
Dabo Xu ◽  
Yanli Zhang ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Food Intake ◽  
Gastric Pacing

Gastric Pacing as Therapy for Morbid Obesity: Preliminary Results

2002 ◽  
Vol 12 (2) ◽  
pp. 12-16 ◽  
Author(s):  
Valerio Cigaina
Keyword(s):  
Morbid Obesity ◽  
Preliminary Results ◽  
Gastric Pacing

scholarly journals High-resolution entrainment mapping of gastric pacing: a new analytical tool

2010 ◽  
Vol 298 (2) ◽  
pp. G314-G321 ◽  
Author(s):  
Gregory O'Grady ◽  
Peng Du ◽  
Wim J. E. P. Lammers ◽  
John U. Egbuji ◽  
Pulasthi Mithraratne ◽  
...  
Keyword(s):  
High Resolution ◽  
Slow Wave ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Field Analysis ◽  
Research Progress ◽  
Multielectrode Arrays ◽  
Gastric Pacing ◽  
Improve Symptom ◽  
Accurate Quantification

Gastric pacing has been investigated as a potential treatment for gastroparesis. New pacing protocols are required to improve symptom and motility outcomes; however, research progress has been constrained by a limited understanding of the effects of electrical stimulation on slow-wave activity. This study introduces high-resolution (HR) “entrainment mapping” for the analysis of gastric pacing and presents four demonstrations. Gastric pacing was initiated in a porcine model (typical amplitude 4 mA, pulse width 400 ms, period 17 s). Entrainment mapping was performed using flexible multielectrode arrays (≤192 electrodes; 92 cm2) and was analyzed using novel software methods. In the first demonstration, entrainment onset was quantified over successive waves in spatiotemporal detail. In the second demonstration, slow-wave velocity was accurately determined with HR field analysis, and paced propagation was found to be anisotropic (longitudinal 2.6 ± 1.7 vs. circumferential 4.5 ± 0.6 mm/s; P < 0.001). In the third demonstration, a dysrhythmic episode that occurred during pacing was mapped in HR, revealing an ectopic slow-wave focus and uncoupled propagations. In the fourth demonstration, differences were observed between paced and native slow-wave amplitudes (0.24 ± 0.08 vs. 0.38 ± 0.14 mV; P < 0.001), velocities (6.2 ± 2.8 vs. 11.5 ± 4.7 mm/s; P < 0.001), and activated areas (20.6 ± 1.9 vs. 32.8 ± 2.6 cm2; P < 0.001). Entrainment mapping enables an accurate quantification of the effects of gastric pacing on slow-wave activity, offering an improved method to assess whether pacing protocols are likely to achieve physiologically and clinically useful outcomes.

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