Bromoderma in a pituitary adenoma patient treated with bromocriptine

2016 ◽  
Vol 44 (5) ◽  
pp. e95-e96 ◽  
Author(s):  
Saki Maeda ◽  
Ikko Kajihara ◽  
Aki Ogata ◽  
Takamitsu Johno ◽  
Masatoshi Jinnin ◽  
...  
Neurosurgery ◽  
2020 ◽  
Vol 87 (2) ◽  
pp. E140-E146 ◽  
Author(s):  
Wende Zhu ◽  
Xing Huang ◽  
Hongyang Zhao ◽  
Xiaobing Jiang

Abstract BACKGROUND AND IMPORTANCE A pituitary adenoma patient who underwent surgery in our department was diagnosed with COVID-19 and 14 medical staff were confirmed infected later. This case has been cited several times but without accuracy or entirety, we feel obligated to report it and share our thoughts on the epidemic among medical staff and performing endonasal endoscopic surgery during COVID-19 pandemic. CLINICAL PRESENTATION The patient developed a fever 3 d post endonasal endoscopic surgery during which cerebrospinal leak occurred, and was confirmed with SARS-CoV-2 infection later. Several medical staff outside the operating room were diagnosed with COVID-19, while the ones who participated in the surgery were not. CONCLUSION The deceptive nature of COVID-19 results from its most frequent onset symptom, fever, a cliché in neurosurgery, which makes it hard for surgeons to differentiate. The COVID-19 epidemic among medical staff in our department was deemed as postoperative rather than intraoperative transmission, and attributed to not applying sufficient personal airway protection. Proper personal protective equipment and social distancing between medical staff contributed to limiting epidemic since the initial outbreak. Emergency endonasal endoscopic surgeries are feasible since COVID-19 is still supposed to be containable when the surgeries are performed in negative pressure operating rooms with personal protective equipment and the patients are kept under quarantine postoperatively. However, we do not encourage elective surgeries during this pandemic, which might put patients in conditions vulnerable to COVID-19.


Author(s):  
Eva Horvath ◽  
Kalman Kovacs ◽  
B. W. Scheithauer ◽  
R. V. Lloyd ◽  
H. S. Smyth

The association of a pituitary adenoma with nervous tissue consisting of neuron-like cells and neuropil is a rare abnormality. In the majority of cases, the pituitary tumor is a chromophobic adenoma, accompanied by acromegaly. Histology reveals widely variable proportions of endocrine and nervous tissue in alternating or intermingled patterns. The lesion is perceived as a composite one consisting of two histogenetically distinct parts. It has been suggested that the neuronal component, morphologically similar to secretory neurons of the hypothalamus, may initiate adenoma formation by releasing stimulatory substances. Immunoreactivity for growth hormone releasing hormone (GRH) in the neuronal component of some cases supported this view, whereas other findings such as consistent lack of growth hormone (GH) cell hyperplasia in the lesions called for alternative explanation.Fifteen tumors consisting of a pituitary adenoma and a neuronal component have been collected over a 20 yr. period. Acromegaly was present in 11 patients, was equivocal in one, and absent in 3.


2017 ◽  
Vol 23 ◽  
pp. 187
Author(s):  
Mindy Griffith ◽  
Padma Raghavan ◽  
Monica Schwarcz ◽  
Michael Goldberg ◽  
Guy Valiquette ◽  
...  
Keyword(s):  

2016 ◽  
Vol 77 (S 01) ◽  
Author(s):  
Martin Rutkowski ◽  
Ryan Alward ◽  
Derek Southwell ◽  
Rebecca Chen ◽  
Jeffrey Wagner ◽  
...  

2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Yuta Murakami ◽  
Shinya Jinguji ◽  
Yugo Kishida ◽  
Taku Sato ◽  
Tadashi Watanabe ◽  
...  

2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Sivashanmugam Dhandapani ◽  
Pinaki Dutta ◽  
Tenzin Gyurmey ◽  
Reema Bansal ◽  
Ashis Pathak ◽  
...  

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