Ero1‐Pdi1 module‐catalyzed dimerization of a nucleotide sugar transporter, FonNst2 , regulates virulence of Fusarium oxysporum on watermelon

2021 ◽  
Author(s):  
Yizhou Gao ◽  
Xiaohui Xiong ◽  
Hui Wang ◽  
Jiajing Wang ◽  
Yan Bi ◽  
...  
Keyword(s):  
Fusarium Oxysporum ◽  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Nucleotide Sugar Transporter

scholarly journals Loss ofsrf-3-encoded Nucleotide Sugar Transporter Activity in Caenorhabditis elegansAlters Surface Antigenicity and Prevents Bacterial Adherence

2004 ◽  
Vol 279 (29) ◽  
pp. 30440-30448 ◽  
Author(s):  
Jörg Höflich ◽  
Patricia Berninsone ◽  
Christine Göbel ◽  
Maria J. Gravato-Nobre ◽  
Brian J. Libby ◽  
...  
Keyword(s):  
Bacterial Adherence ◽  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Nucleotide Sugar Transporter

scholarly journals A hypomorphic allele of SLC35D1 results in Schneckenbecken-like dysplasia

2019 ◽  
Vol 28 (21) ◽  
pp. 3543-3551
Author(s):  
Carsten Rautengarten ◽  
Oliver W Quarrell ◽  
Karen Stals ◽  
Richard C Caswell ◽  
Elisa De Franco ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Missense Variant ◽  
Sugar Transporter ◽  
Loss Of Function ◽  
Transport Activity ◽  
Nucleotide Sugar ◽  
Gene Encoding ◽  
Hypomorphic Allele ◽  
Nucleotide Sugar Transporter

Abstract We report the case of a consanguineous couple who lost four pregnancies associated with skeletal dysplasia. Radiological examination of one fetus was inconclusive. Parental exome sequencing showed that both parents were heterozygous for a novel missense variant, p.(Pro133Leu), in the SLC35D1 gene encoding a nucleotide sugar transporter. The affected fetus was homozygous for the variant. The radiological features were reviewed, and being similar, but atypical, the phenotype was classified as a ‘Schneckenbecken-like dysplasia.’ The effect of the missense change was assessed using protein modelling techniques and indicated alterations in the mouth of the solute channel. A detailed biochemical investigation of SLC35D1 transport function and that of the missense variant p.(Pro133Leu) revealed that SLC35D1 acts as a general UDP-sugar transporter and that the p.(Pro133Leu) mutation resulted in a significant decrease in transport activity. The reduced transport activity observed for p.(Pro133Leu) was contrasted with in vitro activity for SLC35D1 p.(Thr65Pro), the loss-of-function mutation was associated with Schneckenbecken dysplasia. The functional classification of SLC35D1 as a general nucleotide sugar transporter of the endoplasmic reticulum suggests an expanded role for this transporter beyond chondroitin sulfate biosynthesis to a variety of important glycosylation reactions occurring in the endoplasmic reticulum.

scholarly journals Nucleotide Sugar Transporter SLC35 Family Structure and Function

2019 ◽  
Vol 17 ◽  
pp. 1123-1134 ◽  
Author(s):  
Barbara Hadley ◽  
Thomas Litfin ◽  
Chris J. Day ◽  
Thomas Haselhorst ◽  
Yaoqi Zhou ◽  
...  
Keyword(s):  
Family Structure ◽  
Structure And Function ◽  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
And Function ◽  
Nucleotide Sugar Transporter

AtUTr2 is an Arabidopsis thaliana nucleotide sugar transporter located in the Golgi apparatus capable of transporting UDP-galactose

Planta ◽  
2005 ◽  
Vol 222 (3) ◽  
pp. 521-529 ◽  
Author(s):  
Lorena Norambuena ◽  
Ricardo Nilo ◽  
Michael Handford ◽  
Francisca Reyes ◽  
Lorena Marchant ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Golgi Apparatus ◽  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Nucleotide Sugar Transporter

scholarly journals The Human Solute Carrier Gene SLC35B4 Encodes a Bifunctional Nucleotide Sugar Transporter with Specificity for UDP-Xylose and UDP-N-Acetylglucosamine

2005 ◽  
Vol 280 (29) ◽  
pp. 27230-27235 ◽  
Author(s):  
Angel Ashikov ◽  
Françoise Routier ◽  
Jutta Fuhlrott ◽  
Yvonne Helmus ◽  
Martin Wild ◽  
...  
Keyword(s):  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Solute Carrier ◽  
Nucleotide Sugar Transporter

scholarly journals An insight into the orphan nucleotide sugar transporter SLC35A4

2017 ◽  
Vol 1864 (5) ◽  
pp. 825-838 ◽  
Author(s):  
Paulina Sosicka ◽  
Dorota Maszczak-Seneczko ◽  
Bożena Bazan ◽  
Yauhen Shauchuk ◽  
Beata Kaczmarek ◽  
...  
Keyword(s):  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Insight Into ◽  
Nucleotide Sugar Transporter

The nucleotide-sugar transporter family: a phylogenetic approach

Biochimie ◽  
2003 ◽  
Vol 85 (3-4) ◽  
pp. 245-260 ◽  
Author(s):  
Ivan Martinez-Duncker ◽  
Rosella Mollicone ◽  
Patrice Codogno ◽  
Rafael Oriol
Keyword(s):  
Sugar Transporter ◽  
Nucleotide Sugar ◽  
Transporter Family ◽  
Nucleotide Sugar Transporter
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