Being an expert with claim of being specialized in Economic Competitiveness and Innovation Indexes, I felt ashamed of my huge ignorance in endogenous growth theory and its impact on innovation. Therefore, this review holds a good intention for exploring the essence and the unique characters of the endogenous economic growth which focus on the investment in human capital, innovation, and knowledge-based economy which will lead to economic development. The endogenous innovation was tackled in this work of Antonelli (2017) to show the innovation in the creative reactions and as emergent property of the system. The author tried to illustrate the early relation between the early economics of knowledge and economics of growth, after discussing the limits of the new growth theory. The author managed to show the random events of innovation as creative response.