Advanced maternal age increases the risk of very preterm birth, irrespective of parity: a population-based register study

2016 ◽  
Vol 124 (8) ◽  
pp. 1235-1244 ◽  
Author(s):  
U Waldenström ◽  
S Cnattingius ◽  
L Vixner ◽  
M Norman
Keyword(s):  
Preterm Birth ◽  
Maternal Age ◽  
Advanced Maternal Age ◽  
Population Based ◽  
Register Study ◽  
Very Preterm ◽  
Very Preterm Birth

scholarly journals Country of first birth and neonatal outcomes in migrant and Norwegian-born parous women in Norway: a population-based study

2019 ◽  
Author(s):  
Eline Skirnisdottir Vik ◽  
Roy Miodini Nilsen ◽  
Vigdis Aasheim ◽  
Rhonda Small ◽  
Dag Moster ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Population Based ◽  
Neonatal Outcomes ◽  
Migrant Women ◽  
First Birth ◽  
Population Based Study ◽  
Very Preterm ◽  
Very Preterm Birth ◽  
Adverse Neonatal Outcomes ◽  
Moderately Preterm

Abstract Background: This study compares subsequent birth outcomes in migrant women who had already had a child before arriving in Norway with those in migrant women whose first birth occurred in Norway. The aim of this study was to investigate the associations between country of first birth and adverse neonatal outcomes (very preterm birth, moderately preterm birth, post-term birth, small for gestational age, large for gestational age, low Apgar score, stillbirth and neonatal death) in parous migrant and Norwegian-born women. Methods: National population-based study including second and subsequent singleton births in Norway from 1990-2016. Data were retrieved from the Medical Birth Registry of Norway and Statistics Norway. Neonatal outcomes were compared between births to: 1) migrant women with a first birth before immigration to Norway (n=30,062) versus those with a first birth after immigration (n=66,006), and 2) Norwegian-born women with a first birth outside Norway (n=6,205) versus those with a first birth in Norway (n=514,799). Associations were estimated as crude and adjusted odds ratios (aORs) with 95% confidence intervals (CIs) using multiple logistic regression. Results: Migrant women with a first birth before immigrating to Norway had increased odds of adverse outcomes in subsequent births relative to those with a first birth after immigration: very preterm birth (22-31 gestational weeks (gwks); aOR=1.27; CI 1.09-1.48), moderately preterm birth (32-36 gwks; aOR=1.10; CI 1.02-1.18), post-term birth (≥42 gwks; aOR=1.19; CI 1.11-1.27), low Apgar score (<7 at 5 minutes; aOR=1.27; CI 1.16-1.39) and stillbirth (aOR=1.29; CI 1.05-1.58). Similar results were found in the sample of births to Norwegian-born women. Conclusions: The increased odds of adverse neonatal outcomes for migrant and Norwegian-born women who had their first births outside Norway should serve as a reminder of the importance of taking a careful obstetric history in these parous women to ensure appropriate care for their subsequent pregnancies and births in Norway. Keywords: immigration, parous women, neonatal outcomes, obstetric history, predictor

scholarly journals Is IVF/ICSI an Independent Risk Factor for Spontaneous Preterm Birth in Singletons? A Population-Based Cohort Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Nina Jančar ◽  
Barbara Mihevc Ponikvar ◽  
Sonja Tomšič ◽  
Eda Vrtačnik Bokal ◽  
Sara Korošec
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Preterm Birth ◽  
Maternal Age ◽  
Independent Risk Factor ◽  
Very Preterm ◽  
Very Preterm Birth ◽  
History Of ◽  
Uterine Septum ◽  
Uterine Malformations

The aim of our study was to explore the risk factors for very preterm (gestation under 32 weeks) and moderate preterm birth (gestation weeks 32-36 6/7) in singleton pregnancies in a national retrospective cohort study. We also wanted to establish whether IVF/ICSI is an independent risk factor for preterm birth after adjusting for already known confounders. We used data for 267 718 singleton births from 2002-2015 from the National Perinatal Information System of Slovenia, containing data on woman, pregnancy, birth, the postpartum period, and the neonate for each mother–infant pair. Mode of conception, maternal age, education, BMI, parity, smoking, history of cervical excision procedure, history of hysteroscopic resection of uterine septum, presence of other congenital uterine malformations, bleeding in pregnancy, preeclampsia or HELLP and maternal heart, and pulmonary or renal illness were included in the analyses. Unadjusted OR for very preterm birth after IVF-ICSI was 2.8 and for moderate preterm birth was 1.7. After adjusting for known confounders, the OR was still significantly elevated (1.6 and 1.3, respectively). Risk factors for very preterm birth with OR higher than 2.4 were history of cervical excision procedure, resection of uterine septum, operation or having other congenital uterine malformations, and bleeding in pregnancy. Risk factors for very preterm birth with OR between 1.4 and 2.1 were age >35 years, being underweight or obese, not having professional education, smoking, first birth, preeclampsia/HELLP, and IVF/ICSI. Risk factors for moderate preterm birth with OR higher than 2.4 were history of cold knife conization and other congenital uterine malformations. We found that even after adjustment, IVF/ICSI represents a single risk factor for early and late preterm birth even after adjustment with other risks such as maternal age, smoking, or a history of invasive procedures for either cervical intraepithelial neoplasia or infertility treatment.

Early prediction of spontaneous twin very preterm birth: a population based study 2002–2012

2014 ◽  
Vol 28 (15) ◽  
pp. 1784-1789 ◽  
Author(s):  
Tanja Premru-Srsen ◽  
Ivan Verdenik ◽  
Lili Steblovnik ◽  
Helena Ban-Frangez
Keyword(s):  
Preterm Birth ◽  
Population Based ◽  
Early Prediction ◽  
Population Based Study ◽  
Very Preterm ◽  
Very Preterm Birth

scholarly journals Spontaneous very preterm birth in relation to social class, and smoking: a temporal-spatial analysis of routinely collected data in Aberdeen, Scotland (1985–2010)

2019 ◽  
Vol 42 (3) ◽  
pp. 534-541 ◽  
Author(s):  
Stephen J McCall ◽  
David R Green ◽  
Gary J Macfarlane ◽  
Sohinee Bhattacharya
Keyword(s):  
Preterm Birth ◽  
Social Class ◽  
Primary Outcome ◽  
Strong Association ◽  
Population Based ◽  
Maternity Hospital ◽  
Smoking During Pregnancy ◽  
Very Preterm ◽  
Very Preterm Birth ◽  
Deprived Areas

Abstract Objective To examine trends of spontaneous very preterm birth (vPTB) and its relationship with maternal socioeconomic status and smoking. Methods This was a population-based cohort study in Aberdeen Maternity Hospital, UK. The cohort was restricted to spontaneous singleton deliveries occurring in Aberdeen from 1985 to 2010. The primary outcome was very preterm birth which was defined as &lt;32 weeks gestation and the comparison group was deliveries ≥37 weeks of gestation. The main exposures were parental Social Class based on Occupation, Carstairs’ deprivation index and smoking during pregnancy. Logistic regression was used to estimate the association between vPTB and the exposures. Results There was an increased likelihood of vPTB in those with unskilled-occupations compared to professional-occupations [aOR:2.77 (95%CI:1.54–4.99)], in those who lived in the most deprived areas compared to those in the most affluent [aOR: 2.16 (95% CI: 1.27–3.67)] and in women who smoked compared to those who did not [aOR: 1.74 (95% CI: 1.36-2.21)]. The association with Carstairs index was no longer statistically significant when restricted to smokers but remained significant when restricted to non-smokers. Conclusion The strongest risk factor for vPTB was maternal smoking while socioeconomic deprivation showed a strong association in non-smokers. Smoking cessation interventions may reduce vPTB. Modifiable risk factors should be explored in deprived areas.

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