scholarly journals Replication of type 5 adenovirus promotes middle ear infection byStreptococcus pneumoniaein the chinchilla model of otitis media

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Kyle A. Murrah ◽  
Roberta L. Turner ◽  
Bing Pang ◽  
Antonia C. Perez ◽  
Jennifer L. Reimche ◽  
...  
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Ear Infection ◽  
Middle Ear Infection

Middle Ear Infection (Otitis Media)

1990 ◽  
Vol 9 (12) ◽  
pp. 936
Author(s):  
S. Michael Marcy ◽  
Michael E. Pichichero ◽  
Richard H. Schwartz
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Ear Infection ◽  
Middle Ear Infection

scholarly journals Luc Abscess: A Rare Complication of a Common Pediatric Ear Infection

2021 ◽  
Vol 27 (1) ◽  
pp. 20-24
Author(s):  
Nurfadhilah Aisyah Murad ◽  
Zalilah Musa ◽  
Kharudin Abdullah ◽  
Irfan Mohamad
Keyword(s):  
Inflammatory Response ◽  
Bacterial Infection ◽  
Otitis Media ◽  
Middle Ear ◽  
Rare Complication ◽  
Bone Involvement ◽  
Ear Infection ◽  
Temporal Muscle ◽  
Middle Ear Infection ◽  
The Difference

Middle ear infection occurs when fluid accumulate in middle ear as a result of inflammatory response to viral or bacterial infection. Infections may spread from the middle ear, resulting in a subperiosteal collection beneath the temporal muscle. Luc abscess is a rare complication of otitis media. The difference of this complication with other extracranial abscesses relating to otitis media is, it may not be associated with mastoid bone involvement. Therefore, it is defined as benign complication of otitis media. Here, we report a case of 10-month-old baby boy diagnosed with Luc abscess with mastoid involvement.

scholarly journals Vocal Cord Paralysis and Dysphagia as Sequelae of Gradenigo Syndrome

2018 ◽  
Vol 28 (1) ◽  
pp. 15-18
Author(s):  
Mary Ann V. Macasaet ◽  
Emmanuel Tadeus S. Cruz
Keyword(s):  
Vocal Cord ◽  
Otitis Media ◽  
Middle Ear ◽  
Vocal Cord Paralysis ◽  
Petrous Apex ◽  
Suppurative Otitis Media ◽  
Ear Infection ◽  
Nerve Paralysis ◽  
Middle Ear Infection ◽  
Petrous Apicitis

Objectives:     To present a case of vocal cord paralysis and dysphagia developing in Gradenigo syndrome and to discuss its clinical presentation, differential diagnosis and therapeutic approach.   Methods:             Design: Case Report             Setting:  Tertiary Government Hospital             Patient: One   Results:  A 54-year-old lady was admitted with a six month history of left-sided otorrhea, cheek and jaw pain, three months otalgia, and recent-onset hoarseness, dysphagia and diplopia on a background of mastoidectomy at age 6. Otoscopy revealed granulation tissue and chlolesteatoma occupying the left external auditory canal. There was left vocal cord paralysis with pooling of saliva in the pyriform sinus, left lateral gaze paralysis, and left facial nerve paralysis. CT scan revealed sclerosis of the left petrous apex and leptomeningeal enhancement on the left temporal lobe. Chronic suppurative otitis media with cholesteatoma and Gradenigo syndrome was diagnosed, and canal wall down mastoidectomy was performed Postoperatively, the otalgia and pain over the left jaw diminished in intensity while hoarseness and left lateral gaze palsy remained.   Conclusion: Gradenigo syndrome is known for its triad of retro-orbital pain, lateral gaze paralysis, and chronic middle ear infection due to petrous apicitis. Although rare, vocal cord paralysis and dysphagia may develop when infection traverses and encroaches on the jugular foramen where cranial nerves IX, X, and XI are lodged.  Knowledge of the syndrome should not be limited or confined to the classic triad.  Practicing ear specialists should be vigilant and cognizant of the clinical manifestations and sequelae of chronic middle ear infection. Prompt surgical intervention is crucial while resolution of the disease may vary for different individuals.   Keywords: Chronic otitis media, Gradenigo syndrome, vocal cord paralysis, petrous apicitis  

Middle Ear Infection (Otitis Media)

2012 ◽  
pp. 661
Author(s):  
Marc R. Safran ◽  
James Zachazewski ◽  
David A. Stone
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Ear Infection ◽  
Middle Ear Infection

Acute otitis media

2018 ◽  
Vol 11 (6) ◽  
pp. 305-312 ◽  
Author(s):  
John F Curran ◽  
Hannah L Cornwall ◽  
Miklos Perenyei ◽  
Tobias Moorhouse
Keyword(s):  
Primary Care ◽  
Otitis Media ◽  
Middle Ear ◽  
Secondary Care ◽  
Acute Otitis Media ◽  
Common Condition ◽  
Ear Infection ◽  
Diagnosis And Management ◽  
Middle Ear Infection ◽  
Patient Morbidity

Middle ear infection, or acute otitis media (AOM), is a common condition encountered in primary care. Unfortunately, the diagnosis and sequelae of AOM can be overlooked, leading to significant patient morbidity. This article aims to raise awareness of AOM and highlights the relevant anatomy, epidemiology and aetiology. We discuss prevention, diagnosis and management of AOM in primary care, the recognition of complications and when to refer to secondary care.

scholarly journals Experimental Acute Otitis Media Due to Nontypeable Haemophilus influenzae: Comparison of High and Low Azithromycin Doses with Placebo

2002 ◽  
Vol 46 (7) ◽  
pp. 2194-2199 ◽  
Author(s):  
Franz E. Babl ◽  
Stephen I. Pelton ◽  
Zhong Li
Keyword(s):  
Haemophilus Influenzae ◽  
Otitis Media ◽  
Middle Ear ◽  
Clinical Success ◽  
Acute Otitis Media ◽  
Published Data ◽  
Nontypeable Haemophilus Influenzae ◽  
Ear Infection ◽  
Dependent Effect ◽  
Middle Ear Infection

ABSTRACT Treatment of acute otitis media (AOM) with azithromycin results in apparent clinical success, but tympanocentesis performed 4 to 6 days after initiation of therapy in children with nontypeable Haemophilus influenzae (NTHI) recovered from initial middle ear cultures demonstrates persistence of infection in more than 50% of episodes. We sought to determine the effect of azithromycin at different doses on the density of middle ear infection due to NTHI to provide additional understanding of this dichotomy between clinical and microbiologic outcome measures in AOM. In a chinchilla model of experimental otitis media (EOM), animals treated with placebo were compared to animals receiving a single daily dose 30 or 120 mg of azithromycin per kg of body weight per day for 5 days. Microbiologic outcome was assessed by obtaining quantitative cultures from the middle ear during a 5-day course and for 1 week following therapy. Azithromycin concentrations were measured to ascertain whether a concentration-dependent effect was present. Azithromycin at 30 and 120 mg/kg/day demonstrated a dose-dependent effect on the quantitative assessment of middle ear infection due to NTHI. A 30-mg/kg dose of azithromycin daily resulted in levels in serum and areas under the serum concentration-time curve at 24 h comparable to published data obtained with children given azithromycin at 5 to 10 mg/kg in multiday regimens. Increased doses of azithromycin (120 mg/kg) achieved 2.5- to 4-fold-higher levels in serum and 3- to 6-fold-higher total levels and levels in extracellular middle ear fluid as well as more rapid reduction in bacterial density and a greater proportion of middle ears with complete sterilization than either placebo or the 30-mg/kg/day regimen.

scholarly journals Influenza A Virus Alters Pneumococcal Nasal Colonization and Middle Ear Infection Independently of Phase Variation

2014 ◽  
Vol 82 (11) ◽  
pp. 4802-4812 ◽  
Author(s):  
John T. Wren ◽  
Lance K. Blevins ◽  
Bing Pang ◽  
Lauren B. King ◽  
Antonia C. Perez ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Otitis Media ◽  
Influenza A Virus ◽  
Middle Ear ◽  
Influenza A ◽  
Phase Variation ◽  
Infection Model ◽  
Ear Infection ◽  
Middle Ear Infection ◽  
Phase Variants

ABSTRACTStreptococcus pneumoniae(pneumococcus) is both a widespread nasal colonizer and a leading cause of otitis media, one of the most common diseases of childhood. Pneumococcal phase variation influences both colonization and disease and thus has been linked to the bacteria's transition from colonizer to otopathogen. Further contributing to this transition, coinfection with influenza A virus has been strongly associated epidemiologically with the dissemination of pneumococci from the nasopharynx to the middle ear. Using a mouse infection model, we demonstrated that coinfection with influenza virus and pneumococci enhanced both colonization and inflammatory responses within the nasopharynx and middle ear chamber. Coinfection studies were also performed using pneumococcal populations enriched for opaque or transparent phase variants. As shown previously, opaque variants were less able to colonize the nasopharynx.In vitro, this phase also demonstrated diminished biofilm viability and epithelial adherence. However, coinfection with influenza virus ameliorated this colonization defectin vivo. Further, viral coinfection ultimately induced a similar magnitude of middle ear infection by both phase variants. These data indicate that despite inherent differences in colonization, the influenza A virus exacerbation of experimental middle ear infection is independent of the pneumococcal phase. These findings provide new insights into the synergistic link between pneumococcus and influenza virus in the context of otitis media.

scholarly journals Granulation Tissue mimicking a Glomus Tumor in a Patient with Chronic Middle Ear Infection

2016 ◽  
Vol 31 (2) ◽  
pp. 31-35
Author(s):  
Kimberly Mae C. Ong ◽  
Patrick John P. Labra ◽  
Rosario R. Ricalde ◽  
Criston Van C. Manasan ◽  
Jose M. Carnate
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Granulation Tissue ◽  
Glomus Tumor ◽  
University Hospital ◽  
Pulsatile Tinnitus ◽  
Suppurative Otitis Media ◽  
Ear Infection ◽  
Middle Ear Infection ◽  
Glomus Tympanicum

Objective: To present an unusual cause of pulsatile tinnitus, presenting in a young adult suffering from chronic recurrent foul-smelling discharge from the same ear. Methods: Study Design:            Case report Setting:                       Tertiary National University Hospital Patient:                       One   Results: A 24-year old woman presented with pulsatile tinnitus on a background of chronic recurrent foul-smelling discharge. Clinico-radiologic findings seemed consistent with a glomus tympanicum coexisting with chronic suppurative otitis media with cholesteatoma. She underwent tympanomastoidectomy with excision of the mass. Histopathologic evaluation revealed the mass to be granulation tissue. Conclusion: Pulsatile tinnitus is rarely associated with chronic middle ear infection. Granulation tissue arising at the promontory may mimic glomus tumors when accompanied with this symptom. Despite this revelation, it would still be prudent to prepare for a possible glomus tumor intraoperatively, so that profuse bleeding and complications may be avoided. Keywords: tinnitus, pulsatile; otitis media, suppurative; glomus tympanicum

Sign in / Sign up

Export Citation Format

Share Document