In reply: Association between mean systemic filling pressure and acute kidney injury

2021 ◽  
Author(s):  
Jemma Neuman ◽  
Luis F Schulz ◽  
Anders Aneman
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Filling Pressure ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
Systemic Filling Pressure

Systemic filling pressure in intact circulation determined on basis of aortic vs. central venous pressure relationships

1994 ◽  
Vol 267 (6) ◽  
pp. H2255-H2258 ◽  
Author(s):  
E. A. Den Hartog ◽  
A. Versprille ◽  
J. R. Jansen
Keyword(s):  
Central Venous Pressure ◽  
Flow Resistance ◽  
Venous Pressure ◽  
Aortic Pressure ◽  
Filling Pressure ◽  
Central Venous ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
The Mean ◽  
Systemic Filling Pressure

In the intact circulation, mean systemic filling pressure (Psf) is determined by applying a series of inspiratory pause procedures (IPPs) and using Guyton's equation of venous return (Qv) and central venous pressure (Pcv): Qv = a - b x Pcv. During an IPP series, different tidal volumes are applied to set Pcv at different values. From the linear regression between Qv and Pcv, Psf can be calculated as Psf = a/b. Guyton's equation can also be written as Qv = (Psf - Pcv)/Rsd, where Rsd is the flow resistance downstream of the places where blood pressure is equal to Psf. During an IPP, a steady state is observed. Therefore, we can also formulate the following equation for flow: Qs = (Pao - Psf)/Rsu, where Qs is systemic flow, Rsu is the systemic flow resistance upstream to Psf, and Pao is aortic pressure. Because both flows (Qs and Qv) are equal, it follows that Pao = Psf(1 + Rsu/Rsd) - Rsu/Rsd x Pcv. This equation implies a method to determine mean systemic filling pressure on the basis of Pao measurements instead of flow determinations. Using 22 IPPs in 10 piglets, we determined the mean systemic filling pressure, and we compared the values obtained from the flow curves with those obtained from the aortic pressure curves. The mean difference between the two methods was 0.03 +/- 1.16 mmHg. With the use of Pao measurements, the Psf can be estimated as accurately as in using flow determinations. The advantage of the new method is that estimation of cardiac output is not required.

scholarly journals Effect of pneumoperitoneum and steep reverse-Trendelenburg position on mean systemic filling pressure, venous return, and microcirculation during esophagectomy

2018 ◽  
Vol 10 (6) ◽  
pp. 3399-3408 ◽  
Author(s):  
Huaiwu He ◽  
Guillem Gruartmoner ◽  
Yilmaz Ince ◽  
Mark I. van Berge Henegouwen ◽  
Suzanne S. Gisbertz ◽  
...  
Keyword(s):  
Venous Return ◽  
Filling Pressure ◽  
Trendelenburg Position ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
Systemic Filling Pressure ◽  
Reverse Trendelenburg Position

Mean systemic filling pressure as a characteristic pressure for venous return

1985 ◽  
Vol 405 (3) ◽  
pp. 226-233 ◽  
Author(s):  
Adrian Versprille ◽  
Jos R. C. Jansen ◽  
A. Drop ◽  
A. R. Hulsmann
Keyword(s):  
Venous Return ◽  
Filling Pressure ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
Systemic Filling Pressure ◽  
Characteristic Pressure

scholarly journals Changes On Mean Systemic Filling Pressure And Microcirculation After a Fluid Challenge

2015 ◽  
Vol 3 (S1) ◽  
Author(s):  
HD Aya ◽  
A Carsetti ◽  
S Pierantozzi ◽  
J Mellinghof ◽  
N Fletcher ◽  
...  
Keyword(s):  
Fluid Challenge ◽  
Filling Pressure ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
Systemic Filling Pressure

Value and determinants of the mean systemic filling pressure in critically ill patients

2015 ◽  
Vol 309 (5) ◽  
pp. H1003-H1007 ◽  
Author(s):  
Xavier Repessé ◽  
Cyril Charron ◽  
Julia Fink ◽  
Alain Beauchet ◽  
Florian Deleu ◽  
...  
Keyword(s):  
Critically Ill ◽  
Fluid Balance ◽  
Critically Ill Patients ◽  
Filling Pressure ◽  
Time Of Death ◽  
Large Variability ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
A Prospective Study ◽  
Systemic Filling Pressure

Mean systemic filling pressure (Pmsf) is a major determinant of venous return. Its value is unknown in critically ill patients (ICU). Our objectives were to report Pmsf in critically ill patients and to look for its clinical determinants, if any. We performed a prospective study in 202 patients who died in the ICU with a central venous and/or arterial catheter. One minute after the heart stopped beating, intravascular pressures were recorded in the supine position after ventilator disconnection. Parameters at admission, during the ICU stay, and at the time of death were prospectively collected. One-minute Pmsf was 12.8 ± 5.6 mmHg. It did not differ according to gender, severity score, diagnosis at admission, fluid balance, need for and duration of mechanical ventilation, or length of stay. Nor was there any difference according to suspected cause of death, classified as shock (cardiogenic, septic, and hemorrhagic) and nonshock, although a large variability of values was observed. The presence of norepinephrine at the time of death (102 patients) was associated with a higher 1-min Pmsf (14 ± 6 vs. 11.4 ± 4.5 mmHg), whereas the decision to forgo life-sustaining therapy (34 patients) was associated with a lower 1-min Pmsf (10.9 ± 3.8 vs. 13.1 ± 5.3 mmHg). In a multiple-regression analysis, norepinephrine (β = 2.67, P = 0.0004) and age (β = −0.061, P = 0.022) were associated with 1-min Pmsf. One-minute Pmsf appeared highly variable without any difference according to the kind of shock and fluid balance, but was higher with norepinephrine.

scholarly journals Erratum to: Estimation of mean systemic filling pressure in postoperative cardiac surgery patients with three methods

2012 ◽  
Vol 39 (1) ◽  
pp. 163-163
Author(s):  
Jacinta J. Maas ◽  
Michael R. Pinsky ◽  
Bart F. Geerts ◽  
Rob B. de Wilde ◽  
Jos R. Jansen
Keyword(s):  
Cardiac Surgery ◽  
Filling Pressure ◽  
Mean Systemic Filling Pressure ◽  
Systemic Filling ◽  
Systemic Filling Pressure
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